In-stent Carlino—a novel bailout for device-uncrossable in-stent chronic total occlusions - Report - MDSpire

In-stent Carlino—a novel bailout for device-uncrossable in-stent chronic total occlusions

  • By

  • Ahmad Samir

  • Hossameldin Hussein

  • May 12, 2026

  • 0 min

Share

Clinical Report: The In-Stent Carlino Technique for Device-Uncrossable IS-CTOs

Overview

The in-stent Carlino technique provides a safe and effective method for managing device-uncrossable in-stent chronic total occlusions (IS-CTOs), particularly in cases where traditional methods fail.

Background

In-stent chronic total occlusions (IS-CTOs) present significant challenges in coronary interventions, often leading to device uncrossability despite successful wire crossing. This issue is exacerbated by the dense neoatherosclerosis typically found in IS-CTOs, making effective treatment crucial for patient outcomes. The in-stent Carlino technique offers a novel approach to address these challenges, enhancing procedural success and safety.

Data Highlights

No numerical data available in the source material.

Key Findings

['The in-stent Carlino technique effectively addresses device uncrossability in IS-CTOs.', 'Hydraulic plaque modification minimizes the risk of subintimal dissection compared to conventional techniques.', 'Successful device delivery was achieved in both presented cases following the application of the in-stent Carlino technique.', 'The technique benefits from the natural containment provided by the stent framework and dense neoatherosclerotic tissue.', 'IS-CTOs are more likely to present device uncrossability compared to native vessel CTOs due to their pathophysiology.']

Clinical Implications

The in-stent Carlino technique represents a valuable option for interventional cardiologists facing device-uncrossable IS-CTOs, enhancing procedural success rates while maintaining a favorable safety profile, particularly in complex cases with significant neoatherosclerosis.

Conclusion

The in-stent Carlino technique offers a promising solution for managing device-uncrossable IS-CTOs, improving the likelihood of successful interventions. Further exploration into its long-term outcomes and integration into clinical practice is warranted.

Related Resources & Content

  1. Elnur Imanov et al., Proceedings of the PICS-AICS Virtual Symposium, 2020 -- Surgical Treatment of Infants with Critical Aortic Stenosis
  2. Transcarotid Retrograde Stenting Techniques for Treating Stenosis at the Common Carotid Artery Ostium, 2025
  3. Dr. Jimmy Kerrigan, Philips Image Guided Therapy Devices Academy -- Simple Stent Optimization protocol using IVUS
  4. Evaluation and management of patients with coronary chronic total occlusions, 2025
  5. Frontiers | In-Stent Carlino: A Novel Bailout for Device-Uncrossable In-Stent Chronic Total Occlusions, 2025
  6. philips image guided therapy devices academy — Ultra-low contrast PCI case studies in high-risk patients: Techniques and tools to optimize outcomes
  7. Drug-coated balloons and hybrid strategies versus drug-eluting stents in chronic total occlusions: a systematic review and meta-analysis
  8. Evaluation and management of patients with coronary chronic total occlusions considered for revascularisation. A clinical consensus statement of the European Association of Percutaneous Cardiovascular Interventions (EAPCI) of the ESC, the European Association of Cardiovascular Imaging (EACVI) of the ESC, and the ESC Working Group on Cardiovascular Surgery - PubMed
  9. Frontiers | In-Stent Carlino: A Novel Bailout for Device-Uncrossable In-Stent Chronic Total Occlusions

Original Source(s)

Related Content