Morning glory syndrome with retinal detachment and literature review—a case report - Report - MDSpire

Morning glory syndrome with retinal detachment and literature review—a case report

  • By

  • Yanhong Ding

  • Ai Zhang

  • June 16, 2026

  • 0 min

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Clinical Report: Morning Glory Syndrome with Retinal Detachment

Overview

This report details a case of Morning Glory Syndrome (MGS) in a 22-year-old woman, highlighting its association with retinal detachment. The findings underscore the importance of comprehensive ophthalmic evaluation in patients presenting with visual acuity deficits.

Background

Morning Glory Syndrome is a rare congenital optic disc anomaly characterized by significant visual impairment and distinct fundoscopic features. Understanding MGS is crucial for timely diagnosis and management, particularly as it can be associated with serious complications such as retinal detachment.

Data Highlights

No numerical data or trial data presented in the article.

Key Findings

  • MGS is characterized by an enlarged optic disc and abnormal retinal vascularization.
  • The case presented involved a 22-year-old woman with a visual acuity of 0.01 in the affected eye.
  • Retinal detachment was confirmed via optical coherence tomography (OCT).
  • The pathogenesis of MGS remains poorly understood, with various theories regarding its embryonic development.
  • Histopathological findings suggest MGS is a congenital mesodermal lesion rather than a primary optic nerve defect.

Clinical Implications

Clinicians should maintain a high index of suspicion for MGS in patients with unexplained visual deficits, particularly in young individuals. Comprehensive ophthalmic assessments, including imaging, are essential for diagnosing associated complications such as retinal detachment.

Conclusion

Morning Glory Syndrome presents unique challenges in diagnosis and management, particularly when complications like retinal detachment occur. Ongoing research is needed to better understand its pathogenesis and optimize treatment strategies.

Related Resources & Content

  1. Retinal Physician, 2021 -- Postoperative Complications—#ItsComplicated
  2. Optometric Management, 2016 -- CLINICAL: POSTERIOR
  3. Frontiers in Medicine, 2026 -- Case Report: Perifoveal exudative vascular anomalous complex with secondary fundus hemorrhage
  4. Morning Glory Disc Anomaly: Expanding the MR Phenotype - PMC
  5. Surgical challenges in the management of morning glory disc anomaly–associated retinal detachment - PMC
  6. Frontiers in Medicine — Case Report: A case of diffuse subretinal fibrosis and uveitis syndrome with vitreoretinal traction syndrome
  7. Morning Glory Disc Anomaly: Expanding the MR Phenotype - PMC
  8. Surgical challenges in the management of morning glory disc anomaly–associated retinal detachment - PMC
  9. (What's the story) morning glory? MRI findings in morning glory disc anomaly - PubMed

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