Long-term CMR Findings in Pediatric COVID-19 Related Myocarditis - Report - MDSpire

Long-term CMR Findings in Pediatric COVID-19 Related Myocarditis

  • By

  • Ana L. Vasquez Choy

  • Dilachew A. Adebo

  • Mehul D. Patel

  • Santosh C. Uppu

  • Rami M. Kharouf

  • Li Xiong

  • June 18, 2026

  • 0 min

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Clinical Report: Extended CMR Outcomes in Myocarditis Associated with Pediatric COVID-19

Overview

This study evaluates the evolution of cardiac magnetic resonance (CMR) findings in pediatric patients with COVID-19-related myocarditis. It highlights the persistence of CMR abnormalities and their implications for long-term cardiac health in this population.

Background

Myocarditis, particularly in the context of COVID-19, poses significant risks to pediatric patients, potentially leading to severe cardiac dysfunction. Understanding the long-term outcomes of CMR findings is crucial for managing these patients effectively and mitigating future cardiac complications. This study addresses a critical gap in knowledge regarding the persistence of myocardial abnormalities post-COVID-19 infection.

Data Highlights

ParameterValue
Mean Age13.1 years
Male Patients57%
Etiology - MIS-C57%
Etiology - Suspected COVID-1924%
Etiology - Confirmed COVID-1919%

Key Findings

  • All patients had a suspected diagnosis of acute myocarditis, with MIS-C being the most common etiology.
  • Initial CMR findings were generally favorable, indicating a high rate of functional recovery.
  • CMR abnormalities such as late gadolinium enhancement (LGE) may persist for months after clinical resolution.
  • Follow-up CMR studies were conducted in 8 out of 21 patients, indicating the need for longitudinal monitoring.
  • Data suggest that CMR is essential for assessing myocardial inflammation and guiding management in pediatric myocarditis.

Clinical Implications

Healthcare providers should consider regular CMR evaluations for pediatric patients recovering from COVID-19-related myocarditis to monitor for persistent abnormalities. Understanding the potential for long-term CMR findings can inform follow-up care and risk stratification for future cardiac events.

Conclusion

This study underscores the importance of CMR in managing pediatric myocarditis associated with COVID-19, highlighting the need for ongoing monitoring of cardiac health in this vulnerable population.

Related Resources & Content

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  5. 2025 ESC Guidelines for the management of myocarditis and pericarditis | European Heart Journal | Oxford Academic
  6. CMR Findings in the Long-TerM OUtcomes after Multisystem Inflammatory Syndrome In Children (MUSIC) Study - PMC
  7. Post-MIS-C Cardiovascular Outcomes: A Systematic Review - PMC
  8. 2025 ESC Guidelines for the management of myocarditis and pericarditis | European Heart Journal | Oxford Academic
  9. CMR Findings in the Long-TerM OUtcomes after Multisystem Inflammatory Syndrome In Children (MUSIC) Study - PMC
  10. Post-MIS-C Cardiovascular Outcomes: A Systematic Review - PMC

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