Efficacy of plant extracts in heart failure patients: a systematic review and network meta-analysis - Report - MDSpire

Efficacy of plant extracts in heart failure patients: a systematic review and network meta-analysis

  • By

  • Tianjiao Tang

  • Guang Li

  • Xiaoqian Huang

  • Hongsheng Liang

  • June 12, 2026

  • 0 min

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Effectiveness of Botanical Extracts in Patients with Heart Failure

Overview

This comprehensive review and network meta-analysis evaluates the efficacy of various botanical extracts in treating heart failure.

Background

Heart failure (HF) is a prevalent and complex syndrome associated with high morbidity and mortality rates. The increasing global burden of HF necessitates the exploration of effective treatment strategies, particularly adjunctive therapies. Botanical extracts have gained attention as potential complementary treatments due to their natural origin and multi-target effects.

Data Highlights

No numerical data provided in the source material.

Key Findings

  • Heart failure affects over 64 million individuals globally, with increasing prevalence.
  • Ginsenosides improve energy metabolism and exhibit antioxidant properties.
  • Astragaloside IV protects against myocardial ischemia and promotes angiogenesis.
  • Hawthorn extract WS1442 enhances exercise capacity and alleviates symptoms in heart failure patients.
  • Aconite extracts show no significant adverse events compared to controls with long-term use.

Clinical Implications

The findings highlight the potential role of botanical extracts as adjunctive therapies in heart failure management. Clinicians may consider these extracts in conjunction with conventional treatments to enhance patient care.

Conclusion

This review underscores the need for further investigation into the therapeutic efficacy of botanical extracts in heart failure patients. Systematic comparisons among these extracts are essential for optimizing treatment strategies.

Related Resources & Content

  1. Frontiers in Cardiovascular Medicine, 2026 -- The effectiveness and safety of oral Chinese patent medicines in treating myocardial infarction complicated with heart failure: a network meta-analysis of 12 interventions
  2. Frontiers in Cardiovascular Medicine, 2026 -- Evaluation of the therapeutic effect of new hypoglycemic drugs on patients with heart failure with reduced ejection fraction and type 2 diabetes: a systematic review and network meta-analysis
  3. Frontiers in Cardiovascular Medicine, 2026 -- Exercise modalities and dose-response for LVEF Improvement in heart failure patients: a systematic review and network meta-analysis
  4. npj Digital Medicine, 2026 -- Comparative Effectiveness of Telemonitoring Approaches in Heart Failure: A Meta-Analysis of Patient Outcomes
  5. ACC/AHA Task Force on Clinical Practice Guidelines -- 2024 ACC/AHA HF Performance and Quality Measures Update
  6. Nature Medicine, 2024 -- The traditional Chinese medicine Qiliqiangxin in heart failure with reduced ejection fraction: a randomized, double-blind, placebo-controlled trial
  7. BMC Cardiovascular Disorders, 2026 -- Efficacy of plant extracts in heart failure patients: a systematic review and network meta-analysis
  8. ACC/AHA Task Force on Clinical Practice Guidelines
  9. The traditional Chinese medicine Qiliqiangxin in heart failure with reduced ejection fraction: a randomized, double-blind, placebo-controlled trial | Nature Medicine
  10. Efficacy of plant extracts in heart failure patients: a systematic review and network meta-analysis | BMC Cardiovascular Disorders | Springer Nature Link

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