Long-term Results of Malignant Orbital Tumors: A 22-Year Study
Overview
This study evaluates the outcomes of 76 patients with malignant orbital tumors treated at Haukeland University Hospital over 22 years. The study reports a 5-year disease-specific survival rate of 59%, with variations based on tumor type.
Background
Orbital malignancies are rare, with an estimated incidence of 1 in 300,000 individuals. This study provides data from a low-volume center, contributing to the existing literature on malignant orbital tumors.
Data Highlights
Characteristic
Value
Number of Patients
76
Female Patients
41 (54%)
Male Patients
35 (46%)
Median Age at Diagnosis
64 years (3-97 years)
5-Year Survival Rate
59%
Key Findings
Secondary invading tumors were the most common (46% of cases).
Lymphoproliferative diseases had the highest 5-year survival rate at 82%.
Squamous cell carcinoma from paranasal sinuses was the most frequently diagnosed histological subtype (16%).
42 patients (55%) underwent surgical tumor removal, with 55% of these requiring exenteration.
Local radiotherapy was administered to 72% of patients, while 38% received chemotherapy.
42% of patients experienced local/regional relapses or distant metastases.
Clinical Implications
The study highlights the importance of accurate diagnosis and tailored treatment strategies for malignant orbital tumors. The survival rates observed can inform clinical expectations and management approaches for similar cases.
Conclusion
The findings from this study align with international literature regarding malignant orbital tumors.
by Bendik Alvheim Sundfjord, Julie Selvik Bentzon, Signe Johnsen Landa, Svein Arthur Jensen, Dorota Goplen, Jon Espen Dale, Stein Lybak, Hans Olav Ueland, Eyvind Rødahl
