Integrated polyetheretherketone patient-specific implants for multi-subunit midface concavity: a retrospective case series - Report - MDSpire

Integrated polyetheretherketone patient-specific implants for multi-subunit midface concavity: a retrospective case series

  • By

  • Xin Wang

  • Sihan Wu

  • Menghao Wang

  • Tianhang Wu

  • Xiangyu Zheng

  • Fei Li

  • Xiaowei Wang

  • Zhihan Hu

  • Xinyi Chen

  • Qiming Zhao

  • Xiaoping Chen

  • Yue Chen

  • July 7, 2026

  • 0 min

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Clinical Report: Customized Integrated Polyetheretherketone Implants for Midface Concavity

Overview

This study evaluates the feasibility, safety, and aesthetic outcomes of integrated polyetheretherketone (PEEK) implants for correcting multi-subunit midface concavity.

Background

Midface concavity can significantly affect facial aesthetics and balance, particularly in patients without malocclusion. Traditional implants may not adequately address multi-subunit deformities, leading to irregularities in contour and soft tissue. The development of patient-specific implants using CAD/CAM technology offers a potential solution for more effective midfacial augmentation.

Data Highlights

OutcomeResults
Number of implants placed62
Number of patients31
Mean follow-up duration8.3 ± 2.1 months
Patient satisfaction (late follow-up)90.3% satisfied or very satisfied
Transient hypoesthesia38.7% of patients

Key Findings

  • All implant placements were successful with no intraoperative reshaping required.
  • Late postoperative satisfaction scores were significantly higher than early scores (P < 0.01).
  • Transient postoperative edema occurred in all patients.
  • Transient hypoesthesia was reported in 12 patients, resolving within 3 months.
  • No serious complications such as infection or permanent nerve injury were observed.

Clinical Implications

Further studies with longer follow-up, comparative controls, and objective three-dimensional outcome assessment are warranted.

Conclusion

Integrated polyetheretherketone implants appear to be a feasible option for selected patients with multi-subunit midface concavity.

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Original Source(s)

Integrated polyetheretherketone patient-specific implants for multi-subunit midface concavity: a retrospective case series

  • by Xin Wang, Sihan Wu, Menghao Wang, Tianhang Wu, Xiangyu Zheng, Fei Li, Xiaowei Wang, Zhihan Hu, Xinyi Chen, Qiming Zhao, Xiaoping Chen, Yue Chen

  • July 7, 2026

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