Linking Subtypes of Adenomyosis to Coexisting Endometrial Lesions

Overview

This study evaluates the association between diffuse adenomyosis and the risk of coexisting endometrial lesions.

Background

Adenomyosis is a prevalent uterine disorder affecting many reproductive-age women, characterized by the presence of endometrial tissue within the myometrium.

Data Highlights

Key Findings

• Diffuse adenomyosis is associated with a significantly higher incidence of endometrial lesions (49.5%) compared to focal adenomyosis (35.6%).
• After propensity score matching, diffuse adenomyosis remained a significant risk factor for concurrent endometrial lesions (adjusted odds ratio [aOR] = 2.05).
• Subgroup analysis indicated a potentially stronger association in women aged ≤45 years (P < 0.001).
• Prior to matching, patients with diffuse adenomyosis had a higher BMI, greater parity, and more severe pain.
• Diffuse and focal adenomyosis represent distinct clinical phenotypes with different risk profiles for endometrial lesions.

Clinical Implications

Healthcare providers should consider the subtype of adenomyosis when assessing the risk of endometrial lesions in patients. Enhanced surveillance for endometrial pathology is recommended, particularly for women with diffuse adenomyosis.

Conclusion

The study evaluates the association of adenomyosis subtypes with endometrial lesions.

Related Resources & Content

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