A nurse-led bundled care intervention for preventing deep vein thrombosis in immobilized neurosurgical patients: a quasi-experimental study - Report - MDSpire

A nurse-led bundled care intervention for preventing deep vein thrombosis in immobilized neurosurgical patients: a quasi-experimental study

  • By

  • Li Chen

  • Longfen Zhou

  • Ju Huang

  • Mingjie Chen

  • June 1, 2026

  • 0 min

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Clinical Report: Nurse-Directed Care to Prevent DVT in Neurosurgical Patients

Overview

A nurse-led bundled care intervention significantly reduced the incidence of deep vein thrombosis (DVT) in immobilized neurosurgical patients compared to standard care. The intervention also improved patient compliance, knowledge, and satisfaction.

Background

Deep vein thrombosis (DVT) is a serious complication in immobilized neurosurgical patients, with incidence rates significantly higher without effective prophylaxis. Traditional prophylactic measures often fall short due to poor compliance and the risks associated with anticoagulants. A comprehensive, nurse-led approach may enhance prevention strategies and improve patient outcomes.

Data Highlights

OutcomeIntervention GroupControl GroupP-value
DVT Incidence1.66%2.75%0.041
Compliance with GCS/IPC76.5%58.1%<0.001
Early Mobilization72.1%51.5%<0.001
DVT-related Knowledge85.2 ± 8.562.1 ± 10.2<0.001
Limb Circumference Difference1.2 ± 0.8 cm2.1 ± 1.1 cm<0.001
Pain Scores (VAS)2.3 ± 1.24.1 ± 1.6<0.001
Patient Satisfaction94.1 ± 3.385.6 ± 4.8<0.001

Key Findings

  • The intervention group had a significantly lower DVT incidence (1.66% vs. 2.75%, p = 0.041).
  • Compliance with GCS/IPC was higher in the intervention group (76.5% vs. 58.1%, p < 0.001).
  • Early mobilization rates were significantly improved in the intervention group (72.1% vs. 51.5%, p < 0.001).
  • Patients in the intervention group had greater DVT-related knowledge (85.2 ± 8.5 vs. 62.1 ± 10.2, p < 0.001).
  • The intervention group showed a greater reduction in limb circumference difference (1.2 ± 0.8 cm vs. 2.1 ± 1.1 cm, p < 0.001).
  • Patient satisfaction was significantly higher in the intervention group (94.1 ± 3.3 vs. 85.6 ± 4.8, p < 0.001).

Clinical Implications

Implementing a nurse-led bundled care approach can significantly reduce DVT incidence and enhance patient outcomes in immobilized neurosurgical patients. Increased compliance and patient education are critical components of effective DVT prevention strategies.

Conclusion

The study demonstrates that a structured, nurse-led intervention can effectively lower DVT risk and improve clinical outcomes, providing a viable model for VTE prevention in neurosurgical settings.

Related Resources & Content

  1. Banerjee et al., Systematic Review of Thromboembolic Prevention Strategies in Neurosurgery, 2023 -- Thromboembolic prevention strategies
  2. Impact of Early Mobilization on Deep Venous Thrombosis Incidence Following Achilles Tendon Rupture, 2019 -- Early mobilization and DVT
  3. Use of Intermittent Pneumatic Compression for Venous Thromboembolism Prevention in Neurosurgery, 2024 -- IPC in neurosurgery
  4. Venous Thromboembolism Prophylaxis in the Neurocritically Ill Population, 2025 -- VTE prophylaxis in neurocritically ill
  5. Frontiers in Cardiovascular Medicine — Research on interventional treatment strategies for lower extremity deep venous thrombosis based on real-world data
  6. Venous Thromboembolism Prophylaxis in the Neurocritically Ill Population
  7. Effects of intermittent pneumatic compression devices interventions to prevent deep vein thrombosis in surgical patients: A systematic review and meta-analysis of randomized controlled trials
  8. Reducing Missed Doses of VTE Prophylaxis | Venous Thromboembolism | JAMA Surgery | JAMA Network

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