Clinical Report: Risk of Total Knee Arthroplasty After Tibial Plateau Fractures
Overview
This systematic review analyzed 42 studies encompassing 52,577 patients with tibial plateau fractures (TPFs) to determine the risk of conversion to total knee arthroplasty (TKA). The overall conversion rate was found to be 5.1%, which is lower than commonly assumed, with most studies reporting rates between 0% and 10%. Longer follow-up periods and surgical treatment were associated with slightly higher conversion rates.
Background
Tibial plateau fractures involve the proximal tibia and can be treated nonoperatively or operatively, with open reduction and internal fixation (ORIF) as the gold standard surgical method. Posttraumatic osteoarthritis (PTOA) is a frequent complication that may necessitate TKA, which is more challenging after TPF due to factors like stiffness and compromised bone quality. In elderly patients, primary TKA is sometimes considered instead of fixation due to poor bone quality and soft tissue conditions. However, the true risk of TKA following TPF treatment has remained unclear.
Data Highlights
Parameter
Value
Total patients analyzed
52,577
Number of included studies
42
Overall conversion rate to TKA
5.1%
Conversion rate with follow-up <5 years
4.2%
Conversion rate with follow-up >5 years
5.9%
Conversion rate in surgically and non-surgically treated patients
4.6%
Conversion rate in surgically treated patients only
6.3%
Highest reported conversion rate
21.9% (mean follow-up 6.8 years)
Key Findings
The overall conversion rate to TKA after TPF treatment is approximately 5.1%, lower than often assumed.
Most studies (38/42) reported conversion rates between 0% and 10%.
Longer follow-up (>5 years) is associated with a slightly higher conversion rate (5.9%) compared to shorter follow-up (4.2%).
Surgically treated patients have a higher conversion rate (6.3%) than cohorts including non-surgical treatment (4.6%).
Four studies reported no TKA conversions during follow-up, possibly due to small sample sizes or short follow-up periods.
The highest conversion rates reported were 15.5% and 21.9%, but these are outliers without clear explanatory factors.
Clinical Implications
Clinicians can counsel patients with tibial plateau fractures that the risk of requiring total knee arthroplasty is relatively low, around 5%, even after surgical fixation. Longer-term follow-up and surgical treatment slightly increase this risk, but the majority of patients do not progress to TKA. This information supports continued use of ORIF as the standard treatment while considering patient-specific factors such as age and bone quality.
Conclusion
The risk of conversion to total knee arthroplasty following tibial plateau fractures is lower than commonly perceived, with an overall rate near 5%. These findings support the current treatment paradigm favoring fixation procedures while highlighting the need for individualized patient management.
References
Systematic Review 2022 -- Evaluating the Risk of Total Knee Arthroplasty Following Tibial Plateau Fractures
Teriparatide followed by zoledronic acid increased bone mineral density but did not reduce fracture risk compared with standard care in adults with osteogenesis imperfecta.