Transrectal vs. transvaginal oocyte retrieval in patients requesting egg freezing for fertility preservation: a prospective observational study - Report - MDSpire

Transrectal vs. transvaginal oocyte retrieval in patients requesting egg freezing for fertility preservation: a prospective observational study

  • By

  • Nagwan Ahmed Bahgat

  • Shamia Mohamedain Abdelgadir Younis

  • Rehaballa Mohamed Alkatary

  • Abdallah Mohammed Ahmed Ibrahim Mohammed

  • Elsamwael Elhakim

  • Mahmoud Thabet

  • Rayan G. Albarakati

  • Dalia Mahmoud Abdelmonem Elsherbini

  • July 3, 2026

  • 0 min

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Comparative Analysis of Transrectal and Transvaginal Oocyte Retrieval Techniques

Overview

This study evaluates transrectal oocyte retrieval (TROR) as an alternative to transvaginal oocyte retrieval (TVOR) for patients with intact hymens. Results indicate that while TVOR remains the standard method, TROR may be considered for specific patient populations.

Background

Oocyte cryopreservation is a critical assisted reproductive technology that allows women to preserve their fertility for various medical and non-medical reasons. Traditional transvaginal ultrasound-guided retrieval is not suitable for all patients, particularly those with intact hymens. This study aims to provide insights into the efficacy of TROR in comparison to the conventional method.

Data Highlights

ParameterTRORTVOR
Correlation with Age-0.10-0.55
Correlation with BMI-0.20-0.12
Correlation with AMH0.800.40
Correlation with Anesthesia Time0.560.73
Correlation with Surgery Time0.550.74
Correlation with Peak E20.810.80

Key Findings

  • Number of oocytes retrieved negatively correlates with age in both TROR and TVOR groups.
  • AMH levels show a strong positive correlation with the number of oocytes retrieved in TROR.
  • Both retrieval methods demonstrate significant correlations with anesthesia time, surgery time, and peak E2 levels.
  • TROR and TVOR have different correlation strengths with BMI.

Clinical Implications

Understanding the correlations between various factors and oocyte yield can aid in optimizing retrieval strategies.

Conclusion

While transvaginal oocyte retrieval remains the standard, transrectal oocyte retrieval offers an alternative for specific patient populations.

Related Resources & Content

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  3. The Journal of Clinical Endocrinology & Metabolism -- Effects of Negative Pregnancy Experiences in the First IVF Cycle on Future Pregnancy Results
  4. Frontiers in Endocrinology, 2026 -- The predictive value of fresh embryo transfer pregnancy results on frozen embryo transfer outcomes
  5. ESHRE guideline: ovarian stimulation for IVF/ICSI: an update in 2025 - PMC
  6. Recommendations for good practice in ultrasound: oocyte pick up | Human Reproduction Open
  7. Fertility preservation in patients with medical indications: a committee opinion (2026) | American Society for Reproductive Medicine | ASRM
  8. Transrectal oocyte retrieval for fertility preservation in virginal women - ScienceDirect
  9. Frontiers | Transrectal versus transvaginal oocyte retrieval in patients requesting egg freezing for fertility preservation
  10. Transabdominal ultrasound–guided oocyte retrieval for oocyte cryopreservation using a vaginal probe
  11. Egg freezing | HFEA
  12. ESHRE guideline: ovarian stimulation for IVF/ICSI: an update in 2025 - PMC
  13. Recommendations for good practice in ultrasound: oocyte pick up‡ | Human Reproduction Open | Oxford Academic
  14. Fertility preservation in patients with medical indications: a committee opinion (2026) | American Society for Reproductive Medicine | ASRM
  15. Transrectal oocyte retrieval for fertility preservation in virginal women - ScienceDirect
  16. Frontiers | Transrectal versus transvaginal oocyte retrieval in patients requesting egg freezing for fertility preservation: A prospective observational study
  17. Transabdominal ultrasound–guided oocyte retrieval for oocyte cryopreservation using a vaginal probe: a comparison of applicability, effectiveness, and safety with conventional transvaginal approach - PMC
  18. EAU Guidelines on
  19. https://www.indiacode.nic.in/bitstream/123456789/17031/1/aA2021-42.pdf

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