Prevalence of pharmacologically treated attention deficit hyperactivity disorder in children, adolescents, and adults: systematic review and meta-analysis - Report - MDSpire

Prevalence of pharmacologically treated attention deficit hyperactivity disorder in children, adolescents, and adults: systematic review and meta-analysis

  • By

  • Sara Popit

  • Spela Pfeifer

  • Igor Locatelli

  • Matej Stuhec

  • July 10, 2026

  • 0 min

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Clinical Report: Prevalence of Pharmacological Treatment for ADHD

Overview

This systematic review and meta-analysis estimate the prevalence of pharmacologically treated ADHD across various age groups, revealing a pooled prevalence of 73.4%.

Background

Attention deficit hyperactivity disorder (ADHD) is a prevalent neurodevelopmental disorder that often persists into adulthood, affecting multiple domains of functioning. The prevalence of pharmacological treatment for ADHD serves as a critical quality indicator for its management.

Data Highlights

The pooled prevalence of pharmacologically treated ADHD was found to be 73.4% (95% CI: 63.4–81.5), with significant between-study heterogeneity.

Key Findings

  • The systematic review included 13 studies, with 12 contributing to the meta-analysis.
  • Substantial variation in age-specific reporting was noted across studies.
  • The prediction interval for prevalence estimates ranged from 29.6% to 94.5%.
  • No significant geographic variation in treatment prevalence was observed across countries.
  • Sex-stratified analyses indicated no significant differences in treatment rates between males and females.

Clinical Implications

Regular evaluations and adherence to treatment guidelines are essential for ADHD management.

Conclusion

The study highlights the considerable variation in pharmacological treatment prevalence for ADHD.

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  2. Frontiers in Psychiatry, 2026 -- Systematic review of animal studies on the use of herbal medicine for attention-deficit/hyperactivity disorder
  3. BMJ Mental Health, 2026 -- ADHD medication discontinuation and non-adherence: a Norwegian population-based register study
  4. NICE, 2024 -- Recommendations | Attention deficit hyperactivity disorder: diagnosis and management
  5. Frontiers in Psychiatry — Effectiveness of different digital interventions on symptoms for children and adolescents with attention-deficit/hyperactivity disorder: a network meta-analysis
  6. Recommendations | Attention deficit hyperactivity disorder: diagnosis and management | Guidance | NICE
  7. Pharmacological interventions for ADHD: a systematic review and dose–effect network meta-analysis - ScienceDirect
  8. Prevalence of attention deficit hyperactivity disorder/hyperkinetic disorder of pediatric and adult populations in clinical settings: a systematic review, meta-analysis and meta-regression | Molecular Psychiatry

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