Patient-reported and clinical outcomes after first-time atrial fibrillation ablation in older patients: a real-world retrospective single-center study - Report - MDSpire

Patient-reported and clinical outcomes after first-time atrial fibrillation ablation in older patients: a real-world retrospective single-center study

  • By

  • Pernille Borch

  • Ole-Gunnar Anfinsen

  • Finn Hegbom

  • Knut Sevre

  • Torbjørn Holm

  • Trine Synnøve Fink

  • Lars Andreas Dejgaard

  • Erik Kongsgård

  • Mathis Korseberg Stokke

  • Erik Lyseggen

  • July 8, 2026

  • 0 min

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Outcomes Reported by Patients and Clinicians Following Initial Atrial Fibrillation Ablation in Elderly Individuals

Overview

This study evaluates patient-reported outcomes and clinical results following catheter ablation for atrial fibrillation in older patients. A higher recurrence rate was observed in patients aged ≥70 years.

Background

Atrial fibrillation (AF) is increasingly prevalent among older adults, yet this demographic is often underrepresented in clinical studies. Understanding the outcomes of catheter ablation in this population is crucial for informing treatment decisions and improving patient-centered care. Patient-reported outcome measures (PROMs) are essential for assessing the subjective experience of treatment and its impact on quality of life.

Data Highlights

Age GroupΔmEHRAComplication RateAF Recurrence
≥70 years−1.42 ± 1.295%59%
60–65 years−1.78 ± 1.177%47%

Key Findings

  • Both age groups reported significant symptom relief one year after ablation (p < 0.001).
  • The younger group (60–65 years) had a greater absolute reduction in symptoms compared to the older group (p = 0.021).
  • Median mEHRA scores were identical between groups at follow-up, indicating low symptom severity.
  • A greater proportion of older patients reported any improvement in symptoms (p = 0.034).
  • AF recurrence was higher in the older cohort (59% vs 47%, p = 0.042).
  • Complication rates were not significantly different between the two age groups (5% vs 7%, p = 0.62).

Clinical Implications

The findings suggest that catheter ablation can provide meaningful symptom relief for older patients with atrial fibrillation, despite a higher recurrence rate. Clinicians should consider incorporating PROMs into routine assessments to better understand treatment impacts on quality of life.

Conclusion

This study highlights the importance of evaluating both clinical outcomes and patient-reported outcomes in older patients undergoing catheter ablation for atrial fibrillation. The results support the continued use of ablation in this demographic, despite the challenges of higher recurrence rates.

Related Resources & Content

  1. Clinical Research in Cardiology, 2024 -- Impact of Comorbidity on Mortality and Readmission Rates in Patients with Existing Implantable Pacemakers Undergoing Catheter Ablation: Insights from the German Ablation Registry
  2. Clinical Research in Cardiology, 2020 -- Evaluating Safety and Patient-Reported Outcomes in Initial Versus Repeat Ablation for Atrial Fibrillation: Findings from the German Ablation Registry
  3. Frontiers in Medicine, 2026 -- Chronological age was not independently associated with ultra-early safety or arrhythmic outcomes after contemporary atrial fibrillation ablation: a real-world single-center study
  4. Frontiers in Cardiovascular Medicine, 2026 -- Long-term follow-up of patients with pulmonary hypertension after catheter ablation of atrial fibrillation and atrial tachycardia
  5. 2023 Guideline for Diagnosis and Management of Atrial Fibrillation: Key Perspectives - American College of Cardiology
  6. Catheter Ablation Outcomes and Life Expectancy in Very Elderly Atrial Fibrillation Patients: The REHEALTH AF Study
  7. 2023 ACC Guideline for AF Management
  8. Catheter Ablation Outcomes and Life Expectancy in Very Elderly Atrial Fibrillation Patients: The REHEALTH AF Study - ScienceDirect
  9. ESC 365 - Patient-reported outcome measures following pulsed-field ablation versus thermal ablation of atrial fibrillation: results of the prospective PROMs-PFA study

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