Insurance Coverage and Access Requirements for Lower-Emission Inhalers in US Commercial Health Plans - Report - MDSpire
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Access and Insurance Coverage for Low-Emission Inhalers in Commercial Health Plans in the United States

  • By

  • Ashwaghosha Parthasarathi

  • Paras Modha

  • Adithi Chellappan

  • Chloe Kline

  • Reynold A. Panettieri

  • Soko Setoguchi

  • September 28, 2026

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Access and Insurance Coverage for Low-Emission Inhalers in Commercial Health Plans

Overview

This study evaluates the formulary coverage and patient cost-sharing for low-emission inhalers in US commercial health plans, highlighting disparities in coverage between propellant-containing metered-dose inhalers (MDIs) and propellant-free alternatives like dry powder inhalers (DPIs) and soft mist inhalers (SMIs).

Background

Asthma and chronic obstructive pulmonary disease (COPD) are major respiratory conditions treated with inhalers, which can have substantial environmental impacts due to their propellants. The accessibility of inhalers is often influenced by insurance formulary decisions, which can limit patient access to lower-emission alternatives. Understanding these coverage patterns is crucial for promoting environmentally friendly inhaler options.

Data Highlights

Therapeutic ClassMDI Coverage (%)DPI/SMI Coverage (%)
SABAs99.633.2
ICS99.489.5
ICS-LABAs99.182.6

Key Findings

  • Nearly all commercial plans cover propellant-containing MDIs across therapeutic classes (SABAs: 99.6%, ICS: 99.4%, ICS-LABAs: 99.1%).
  • Only 33.2% of plans cover a propellant-free DPI or SMI for SABAs.
  • Lower-barrier access for propellant-free devices is significantly less common compared to MDIs, with only 7.8% for SABAs.
  • Among ICS and ICS-LABAs, coverage of both device types is more prevalent, with 89.3% and 82.0% respectively.
  • Approximately 97% of inhaler-associated greenhouse gas emissions in the US derive from SABAs, ICS, and ICS-LABAs.
  • Coverage obstacles favoring MDIs are evident across the US insurance landscape, similar to findings in Medicare plans.

Clinical Implications

Clinicians should be aware of disparities in insurance coverage for inhalers when prescribing.

Conclusion

This study reveals critical gaps in insurance coverage for low-emission inhalers, particularly for SABAs, which may hinder efforts to reduce inhaler-related greenhouse gas emissions.

Related Resources & Content

  1. JAMA Network Open, 2023 -- Access and Insurance Coverage for Low-Emission Inhalers
  2. JAMA Network Open — Analysis of Inhaler Device Utilization, Out-of-Pocket Expenses by Insurance Type, and Projected Carbon Dioxide Emissions
  3. JAMA Network Open — Environmental Effects of Inhaler Formulations
  4. American Association for Respiratory Care (AARC) — Inhaler Utilization Differs According to Race, Economic Factors
  5. Drugs - Real World Outcomes — Analysis of Medication Utilization and Expenses for Respiratory Care Under Colombia's 2022 Health Benefit Plan
  6. 2026 GINA Summary Guide - Global Initiative for Asthma
  7. GOLD 2026 Pocket Guide
  8. Insurance Coverage and Access Requirements for Lower-Emission Inhalers in US Commercial Health Plans | Health Policy | JAMA Network Open | JAMA Network

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