The therapeutic effect of IPL on children with vernal keratoconjunctivitis - Report - MDSpire

The therapeutic effect of IPL on children with vernal keratoconjunctivitis

  • By

  • Jiao Jiang

  • Shaoyi Wang

  • Shaohua Chen

  • Shuoshuo Meng

  • Yang Yang

  • June 22, 2026

  • 0 min

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Clinical Report: Evaluating the Impact of Intense Pulsed Light Therapy on Pediatric Vernal Keratoconjunctivitis

Overview

This study evaluates the effectiveness of intense pulsed light (IPL) therapy as an adjunct treatment for vernal keratoconjunctivitis (VKC) in children.

Background

Vernal keratoconjunctivitis (VKC) is a chronic inflammatory eye condition that predominantly affects children and adolescents, leading to significant discomfort and recurrent episodes. Current treatments primarily involve long-term use of eye drops, which do not prevent recurrence. The introduction of IPL therapy offers a potential adjunctive treatment option.

Data Highlights

GroupNumber of PatientsRecurrence IntervalAdverse Reactions
IPL Group27ExtendedNone
Control Group35Not ExtendedNone

Key Findings

  • IPL treatment significantly extended the recurrence interval of VKC (log-rank P = 0.003).
  • No statistically significant difference in treatment course duration between IPL and control groups (P > 0.05).
  • Both treatment groups reported no adverse reactions during the study.
  • Conventional drug therapy was used in both groups, including antihistamines and glucocorticoids.

Clinical Implications

The findings suggest that IPL can be safely integrated into treatment regimens for children with VKC, potentially improving management of recurrence. Clinicians may consider IPL as an adjunctive therapy alongside conventional treatments.

Conclusion

IPL therapy shows a significant impact on prolonging recurrence intervals.

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  4. PubMed, Effectiveness of Corticosteroid-Sparing Topical Treatments for Vernal Keratoconjunctivitis in Children, 2026
  5. PubMed, The impact of tacrolimus therapy on the outcomes of vernal keratoconjunctivitis: a systematic review and meta-analysis, 2026
  6. Frontiers, The therapeutic effect of IPL on children with vernal keratoconjunctivitis, 2026
  7. Ophthalmology Management — Adding Interventional DED Treatment to Your Practice
  8. Effectiveness of Corticosteroid-Sparing Topical Treatments for Vernal Keratoconjunctivitis in Children: A Report by the American Academy of Ophthalmology - PubMed
  9. The impact of tacrolimus therapy on the outcomes of vernal keratoconjunctivitis: a systematic review and meta-analysis - PubMed
  10. Frontiers | The therapeutic effect of IPL on children with vernal keratoconjunctivitis

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