Occupational burnout and risk of suicidality in healthcare professionals: a PRISMA-guided systematic review - Report - MDSpire

Occupational burnout and risk of suicidality in healthcare professionals: a PRISMA-guided systematic review

  • By

  • Alexandru Ungurianu

  • Virginia Marina

  • July 14, 2026

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Clinical Report: The Link Between Occupational Burnout and Suicidal Risk

Overview

This systematic review identifies an association between burnout and suicidality among healthcare professionals, highlighting emotional exhaustion and depersonalization as predictors. Vulnerable subgroups include nurses, physicians, women clinicians, and younger professionals.

Background

Burnout is recognized as a threat to the mental health of healthcare professionals, resulting from chronic workplace stress. Understanding the link between burnout and suicidality is essential for developing effective interventions.

Data Highlights

Study TypeNumber of StudiesMeta-Analysis Included
Systematic Review2910

Key Findings

  • Associations were observed between burnout and suicidality.
  • Emotional exhaustion and depersonalization are predictors of suicidality.
  • Reduced personal accomplishment showed weaker or inverse associations with suicidality.
  • Nurses and physicians are identified as vulnerable to burnout-related suicidality.
  • Higher effect sizes were reported in pandemic-era studies compared to pre-pandemic research.
  • Methodological quality of included studies was moderate to high, with heterogeneity explained by profession, region, and burnout instrument used.

Clinical Implications

Healthcare organizations should ensure access to mental health support for their staff.

Conclusion

The findings highlight the need for integrated strategies within occupational health frameworks to safeguard clinician wellbeing.

Related Resources & Content

  1. Journal of General Internal Medicine, 2021–2024 -- Prevalence and Treatment of Anxiety and Depression Among US Healthcare Workers
  2. BMC Psychiatry, 2025 -- Three years of pandemic stress and staffing challenges: a retrospective qualitative study of COVID-19 impacts on frontline healthcare workers’ mental health and wellbeing
  3. Surgeons in the UK, 2021 -- Surgeons in the UK Experience Burnout During the COVID-19 Pandemic: Findings from a Cohort Study
  4. Journal of General Internal Medicine, 2026 -- Differential Impact of a Digital Mental Health Engagement Platform on Black and Female Health Care Workers: A Secondary Analysis of a Randomized Trial
  5. WHO guidelines on mental health at work, NCBI Bookshelf -- Recommendations
  6. Frontiers in Psychiatry, 2026 -- Occupational Burnout and Risk of Suicidality in Healthcare Professionals: A PRISMA-Guided Systematic Review
  7. Recommendations - WHO guidelines on mental health at work - NCBI Bookshelf
  8. Frontiers | Occupational Burnout and Risk of Suicidality in Healthcare Professionals: A PRISMA-Guided Systematic Review

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