Determinants of growth parameters at 12-month corrected age among very preterm infants in China: a retrospective cohort study - Report - MDSpire

Determinants of growth parameters at 12-month corrected age among very preterm infants in China: a retrospective cohort study

  • By

  • Wenting Zheng

  • Youjiong Wang

  • Jinfeng Liu

  • Lei Ye

  • Yuanyuan Zhang

  • Jie Cao

  • Lijin Zhao

  • July 6, 2026

  • 0 min

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Factors Influencing Growth Metrics at 12-Month Corrected Age in Very Preterm Infants in China

Overview

This study investigates the growth metrics of very preterm infants (VPI) in China, identifying key maternal and clinical factors that influence physical growth outcomes within the first 12 months of corrected age.

Background

Preterm birth is a significant contributor to neonatal mortality and morbidity, particularly affecting very preterm infants who are at high risk for growth failure and developmental challenges. This study provides insights into the specific risk factors associated with growth metrics in VPI.

Data Highlights

No numerical data provided in the source material.

Key Findings

  • Maternal postnatal depression is a significant risk factor for poor growth outcomes in VPI (p < 0.05).
  • Clinical hypothyroidism in mothers is associated with adverse growth metrics in infants.
  • Gestational diabetes mellitus (GDM) and preeclampsia are linked to poorer growth in VPI.
  • Congenital heart diseases in VPI negatively impact physical growth.
  • Girls with higher gestational age and birth weight, as well as those receiving exclusive breastfeeding, show better growth outcomes.

Clinical Implications

Healthcare providers should consider maternal mental health and pregnancy complications when assessing growth in very preterm infants. Targeted interventions addressing these factors may enhance growth outcomes in this vulnerable population.

Conclusion

The study underscores the importance of addressing maternal and infant-specific risk factors to promote better growth in very preterm infants. Further research is needed to develop effective interventions.

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  8. Growth monitoring technical guide 0.1.indd
  9. Assessment of growth status and nutritional management of prematurely born infants after hospital discharge: A position paper of the ESPGHAN Nutrition Committee - PubMed
  10. Growth and human milk intake outcomes from postdischarge feedings among very-low-birth-weight preterm infants: A systematic review - PubMed

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