Clinical Report: Impact of Walking Exercise on Cardiorespiratory Fitness in Cancer
Overview
This systematic review and meta-analysis evaluated the effects of walking exercise on cardiorespiratory fitness (CRF) in cancer patients. Findings indicate that walking training significantly improves peak oxygen uptake and reduces fatigue.
Background
Cancer patients often experience impaired cardiorespiratory fitness due to treatments like chemotherapy and radiation, which can lead to increased mortality risk and decreased quality of life. Exercise, particularly walking, is a low-cost and accessible intervention.
Data Highlights
Outcome
Effect Size (SMD/MD)
95% CI
P-value
VO2 peak
0.56
[0.06, 1.06]
0.03
Fatigue
-0.45
[-0.71, -0.18]
0.001
VO2 max
0.20
[-0.15, 0.54]
0.26
6MWD
53.97
[-23.00, 130.93]
0.17
Dyspnea
-0.18
[-0.47, 0.11]
0.23
Key Findings
Walking training significantly improved VO2 peak (SMD = 0.56; P = 0.03).
Walking training significantly reduced fatigue (SMD = -0.45; P = 0.001).
No significant effects were found for VO2 max (SMD = 0.20; P = 0.26).
No serious adverse events related to walking interventions were reported.
Clinical Implications
Walking training may serve as a beneficial intervention to enhance cardiorespiratory fitness and reduce fatigue in cancer patients. Clinicians should consider incorporating walking programs into treatment plans while recognizing the need for further high-quality trials.
Conclusion
Walking training may improve VO2 peak and reduce fatigue in cancer patients.
