Effects of modified uvulopalatopharyngoplasty combined with pharyngeal and genioglossus exercises on sleep quality, cognitive function, and quality of life in patients with obstructive sleep apnea-hypopnea syndrome: a retrospective study - Report - MDSpire

Effects of modified uvulopalatopharyngoplasty combined with pharyngeal and genioglossus exercises on sleep quality, cognitive function, and quality of life in patients with obstructive sleep apnea-hypopnea syndrome: a retrospective study

  • By

  • Pingping Zhang

  • Dawei Liang

  • June 1, 2026

  • 0 min

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Clinical Report: Impact of Enhanced Uvulopalatopharyngoplasty on OSAHS

Overview

This study evaluates the effects of modified uvulopalatopharyngoplasty combined with pharyngeal and genioglossus exercises on sleep quality, cognitive performance, and quality of life in patients with obstructive sleep apnea-hypopnea syndrome (OSAHS). Results indicate significant improvements in these areas compared to conventional postoperative training.

Background

Obstructive sleep apnea-hypopnea syndrome (OSAHS) is a prevalent disorder that can lead to serious health consequences, including increased mortality rates. Surgical interventions like modified uvulopalatopharyngoplasty (UPPP) aim to alleviate upper airway obstruction, but their effectiveness can be limited. This study explores the potential benefits of combining UPPP with targeted muscle exercises to enhance surgical outcomes and overall patient well-being.

Data Highlights

GroupUpper Airway RemodelingRespiratory PressureSleep QualityCognitive FunctionQuality of Life
Study Group (n=45)ImprovedImprovedBetterImprovedImproved
Control Group (n=54)Less ImprovementLess ImprovementWorseLess ImprovementLess Improvement

Key Findings

  • The study group showed significantly better upper airway remodeling compared to the control group (P < 0.05).
  • Respiratory pressure was improved in the study group postoperatively.
  • Sleep quality, as assessed by self-rating, was superior in the study group (P < 0.05).
  • Cognitive function improvements were noted in the study group relative to the control group.
  • A greater proportion of patients in the study group rated their sleep quality as 'good' or 'very good' compared to the control group.

Clinical Implications

The findings suggest that incorporating pharyngeal and genioglossus exercises into postoperative care for OSAHS patients may enhance recovery outcomes. Clinicians should consider this combined approach to improve sleep quality and cognitive function following UPPP.

Conclusion

The combination of modified UPPP with targeted muscle exercises appears to yield significant benefits in sleep quality and overall patient outcomes in OSAHS. Further research may be warranted to validate these findings.

Related Resources & Content

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  4. Current guideline positions, VA/DoD Clinical Practice Guideline, 2025 -- Insufficient evidence for myofunctional exercise
  5. Efficacy of myofunctional therapy for obstructive sleep apnea: A systematic review and network meta-analysis, ScienceDirect, 2025
  6. Effectiveness of Palatopharyngeal Surgery Modifications in Obstructive Sleep Apnea: A Meta-analysis, PubMed, 2025
  7. conexiant — A Smarter Screen for Sleep Apnea Stimulation
  8. https://www.healthquality.va.gov/guidelines/CD/insomnia/I-OSA-CPG_2025-Guideline_final_20250915.pdf
  9. Efficacy of myofunctional therapy for obstructive sleep apnea: A systematic review and network meta-analysis - ScienceDirect
  10. Effectiveness of Palatopharyngeal Surgery Modifications in Obstructive Sleep Apnea: A Meta-analysis - PubMed

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