The effect of acceptance and commitment therapy on negative emotions and quality of life in stroke patients: a systematic review and meta-analysis - Report - MDSpire

The effect of acceptance and commitment therapy on negative emotions and quality of life in stroke patients: a systematic review and meta-analysis

  • By

  • Yana Wang

  • Boling Wei

  • Lu Wang

  • Chun Huang

  • Jifeng Rong

  • Tianbao Sun

  • Yu Liu

  • May 18, 2026

  • 0 min

Share

Clinical Report: Impact of Acceptance and Commitment Therapy on Stroke Survivors

Overview

This systematic review and meta-analysis found that Acceptance and Commitment Therapy (ACT) significantly reduces depression and anxiety while improving quality of life in stroke survivors. The findings suggest that ACT may be a beneficial intervention in post-stroke rehabilitation.

Background

Stroke is a leading cause of disability, often resulting in emotional disturbances such as depression and anxiety, which can hinder rehabilitation and quality of life. With a high prevalence of these emotional disorders among stroke survivors, effective psychological interventions are crucial for improving patient outcomes. Acceptance and Commitment Therapy (ACT) offers a unique approach by promoting psychological flexibility, which may be particularly beneficial for this population.

Data Highlights

OutcomeStandardized Mean Difference (SMD)95% Confidence Interval (CI)p-value
Depression-1.37-1.86 to -0.87< 0.00001
Anxiety-1.25-1.76 to -0.74< 0.00001
Quality of Life1.360.69 to 2.02< 0.0001

Key Findings

  • ACT significantly alleviated depression in stroke survivors (SMD = -1.37).
  • ACT significantly reduced anxiety levels (SMD = -1.25).
  • Quality of life was significantly enhanced by ACT (SMD = 1.36).
  • Secondary outcomes improved, including psychological flexibility and self-efficacy.
  • ACT may help reduce avoidance behaviors and enhance resilience in stroke patients.

Clinical Implications

Healthcare providers should consider incorporating ACT into rehabilitation programs for stroke survivors to address emotional well-being and improve quality of life. Given the significant impact of depression and anxiety on recovery, integrating psychological therapies like ACT can be a vital component of comprehensive stroke care.

Conclusion

ACT is an effective intervention for alleviating negative emotions and enhancing quality of life in stroke survivors. Future research should focus on larger, standardized trials to further validate these findings.

Related Resources & Content

  1. Liu et al., Frontiers in Neurology, 2026 -- The effect of acceptance and commitment therapy on negative emotions and quality of life in stroke patients: a systematic review and meta-analysis
  2. NICE, Recommendations | Stroke rehabilitation in adults, 2023 -- Guidance
  3. Frontiers in Psychiatry, 2026 -- Effectiveness of mindfulness-based stress reduction for depression in post-stroke patients: a systematic review and meta-analysis
  4. Frontiers in Medicine, 2026 -- Effectiveness of different types of exercise therapy in improving post-stroke depression: a systematic review and network meta-analysis
  5. Frontiers in Surgery, 2026 -- Analysis: The Integration of Acceptance and Commitment Therapy with Standard Care Enhances Psychosocial Well-being and Lowers Complications in Patients with Permanent Colostomies Post-Colorectal Cancer Surgery
  6. Frontiers in Oncology — Effects of different exercise interventions on quality of life in breast cancer survivors after treatment: a systematic review and network meta-analysis
  7. NICE Guidance on Stroke Rehabilitation
  8. Frontiers | The effect of acceptance and commitment therapy on negative emotions and quality of life in stroke patients: a systematic review and meta-analysis

Original Source(s)

Related Content