Psychological Stress, Self-Reported Anxiety, and Depression in Women Diagnosed with Takotsubo Syndrome - Report - MDSpire

Psychological Stress, Self-Reported Anxiety, and Depression in Women Diagnosed with Takotsubo Syndrome

  • By

  • Runa Sundelin

  • Christina Ekenbäck

  • Jonas Spaak

  • Peder Sörensson

  • Loghman Henareh

  • Per Tornvall

  • Patrik Lyngå

  • January 19, 2026

  • 0 min

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Psychological Stress, Self-Reported Anxiety, and Depression in Women Diagnosed with Takotsubo Syndrome

Overview

This study investigates the psychological stress, anxiety, and depression levels in women diagnosed with Takotsubo syndrome six months post-event. It highlights the significant psychological burden faced by these patients compared to age-matched healthy women.

Background

Incorporate specific references to studies that support claims about anxiety and depression levels.

Data Highlights

No numerical data or trial data was provided in the article.

Key Findings

  • Takotsubo syndrome is primarily diagnosed in women, with a significant psychological burden observed.
  • Patients with takotsubo syndrome report higher levels of depressive symptoms and illness-related anxiety compared to healthy controls.
  • There is a lack of significant differences in awakening salivary cortisol levels between women with takotsubo syndrome and healthy women.
  • High levels of self-rated stress were noted in patients with takotsubo syndrome.
  • The study suggests that psychological stress may reflect a long-term state of burden in these patients.

Clinical Implications

Healthcare providers should be aware of the psychological impacts of takotsubo syndrome on female patients. Screening for anxiety and depression should be integrated into the management plan to improve overall patient outcomes.

Conclusion

The findings underscore the need for comprehensive psychological assessment and support for women diagnosed with takotsubo syndrome, as they may experience significant mental health challenges post-event.

Related Resources & Content

  1. Kastaun et al., Clinical Research in Cardiology, 2020 -- Psychological Impact of SARS-CoV-2 Infection Leading to Takotsubo Cardiomyopathy
  2. European Journal of Preventive Cardiology, 2022 -- Mental health status and quality of life after an acute myocardial infarction with non-obstructive coronary arteries or takotsubo syndrome: a systematic review
  3. Clinical Research in Cardiology, 2025 -- Comparative Analysis of Temporal Changes in Cardiac Function Between Women with Takotsubo Syndrome and Anterior STEMI
  4. Acta Neurochirurgica, 2026 -- Pressor use and its impact on outcomes in aneurysmal subarachnoid hemorrhage patients with takotsubo cardiomyopathy: a quantitative analysis
  5. 2025 ACC/AHA/ACEP/NAEMSP/SCAI Guideline for the Management of Patients With Acute Coronary Syndromes
  6. 2025 ESC Clinical Consensus Statement on mental health and cardiovascular disease
  7. 2025 ACC/AHA/ACEP/NAEMSP/SCAI Guideline for the Management of Patients With Acute Coronary Syndromes: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines - PubMed

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