Efficacy and safety of low- and high-intensity magnetic field therapies for orthopedic pain: a systematic review - Report - MDSpire

Efficacy and safety of low- and high-intensity magnetic field therapies for orthopedic pain: a systematic review

  • By

  • Ludimila Dias Silva

  • Joelington Dias Batista

  • Jobson Dias Batista

  • Gabrielly Santos Pereira

  • Marcelo Lourenço da Silva

  • April 30, 2026

  • 0 min

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Clinical Report: Assessment of Low-Intensity and High-Intensity Magnetic Field Therapies

Overview

This systematic review evaluates the efficacy and safety of low-intensity pulsed electromagnetic field therapy (PEMF) and high-intensity repetitive peripheral magnetic stimulation (rPMS) for orthopedic pain. Findings indicate that both therapies can reduce pain and improve functional outcomes without serious adverse events.

Background

Orthopedic and musculoskeletal pain is a significant cause of disability, affecting quality of life and healthcare costs. Traditional treatments often provide limited relief, highlighting the need for effective non-invasive therapies. Magnetic field therapies, such as PEMF and rPMS, have emerged as potential adjunctive treatments for pain modulation and functional improvement.

Data Highlights

Study TypeNumber of RCTsKey Outcomes
Systematic Review8Reduction in pain, improvement in functional outcomes

Key Findings

  • PEMF is associated with sustained analgesic and anti-inflammatory effects.
  • rPMS provides faster pain reduction through neuromuscular activation.
  • Both therapies showed improvements in the Oswestry Disability Index and WOMAC scores.
  • No serious adverse events were reported in the included studies.
  • Higher stimulation intensities or combined therapy with exercise may enhance benefits.

Clinical Implications

Magnetic field therapies can be considered as safe adjunctive options for managing musculoskeletal pain. Clinicians should evaluate the potential benefits of these therapies in conjunction with traditional treatment modalities, especially in patients with chronic pain conditions.

Conclusion

Magnetic field therapies demonstrate promise in alleviating orthopedic pain and improving function, warranting further investigation through larger, standardized trials to optimize treatment protocols.

References

  1. Frontiers in Neurology, 2023 -- Efficacy and safety of magnetic resonance-guided focused ultrasound for Parkinson's disease: a systematic review and meta-analysis
  2. Pain Medicine, 2023 -- Systematic review and meta-analysis of conventional medical management in a patient population with refractory chronic pain suitable to receive a spinal cord stimulation system
  3. European Radiology, 2024 -- Key Insights on MR Safety for At-Risk Populations: Recommendations from the European Society for Magnetic Resonance in Medicine and Biology
  4. Pain Medicine, 2023 -- Noninvasive brain stimulation beyond the motor cortex: a systematic review and meta-analysis exploring effects on quantitative sensory testing in clinical pain
  5. Frontiers, 2026 -- Efficacy and safety of low-and high-intensity magnetic field therapies for orthopedic pain: a systematic review
  6. AAOS Guidelines on Osteoarthritis of the Knee
  7. Frontiers | Efficacy and safety of low-and high-intensity magnetic field therapies for orthopedic pain: a systematic review

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