Left ventricular longitudinal function and hyperkinetic profile: a new echo world to explore? - Report - MDSpire
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Exploring Left Ventricular Longitudinal Function and Hyperkinetic Characteristics: A New Frontier in Echocardiography?

  • By

  • Filipe André Gonzalez

  • Siddharth Dugar

  • Michel Slama

  • Filippo Sanfilippo

  • August 13, 2026

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Clinical Report: Exploring Left Ventricular Longitudinal Function and Hyperkinetic Characteristics

Background

Assessing LV function is crucial in critically ill patients, particularly in the ICU setting where timely and accurate evaluations can influence management decisions. Traditional reliance on LVEF has been challenged by emerging evidence suggesting that other parameters, such as global longitudinal strain (GLS), may better predict outcomes.

Data Highlights

No numerical data available in the provided source.

Key Findings

  • LVEF measured by Simpson’s method does not correlate with mortality in critically ill patients.
  • Global longitudinal strain (GLS) may offer superior prognostic information compared to LVEF.
  • A hyperdynamic LV state (LVEF ≥ 70%) is associated with increased in-hospital mortality.
  • Early dynamic left intraventricular obstruction has a reported incidence of 22% in septic shock patients.
  • Longitudinal markers such as MAPSE and TDI-S’ may aid in diagnosing LV hyperdynamic profiles.
  • A U-shaped relationship exists between LVEF and mortality in critical illness.

Clinical Implications

Consideration of longitudinal markers like GLS, MAPSE, and TDI-S’ in routine assessments of LV function in critically ill patients is suggested.

Conclusion

The findings from this study underscore the need for a shift towards evaluating LV longitudinal function in critically ill patients, as it may enhance prognostic accuracy and guide clinical decision-making.

Related Resources & Content

  1. Cavefors et al., Frontiers in Cardiovascular Medicine, 2026 -- Exploring Left Ventricular Longitudinal Function and Hyperkinetic Characteristics
  2. Dugar et al., Journal of Cardiothoracic Surgery, 2026 -- Prognostic value of left ventricular ejection fraction and global longitudinal strain for short-term mortality in sepsis
  3. American Society of Echocardiography, 2025 -- Clinical Applications of Strain Echocardiography: A Clinical Consensus Statement
  4. Clinical Research in Cardiology — Evaluation of Atrial Conduit Function: Introducing a Novel Index for Diastolic Dysfunction Assessment
  5. Clinical Research in Cardiology — Strategies to Prevent Common Mistakes in Left Heart Echocardiography: Recommendations from the German Cardiovascular Ultrasound Working Group
  6. Clinical Research in Cardiology — Link Between Left Atrial Phasic Conduit Function and Early Recurrence of Atrial Fibrillation Post-Electrical Cardioversion
  7. Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock 2026
  8. Clinical Applications of Strain Echocardiography: A Clinical Consensus Statement From the American Society of Echocardiography Developed in Collaboration With the European Association of Cardiovascular Imaging of the European Society of Cardiology
  9. Prognostic value of left ventricular ejection fraction and global longitudinal strain for short-term mortality in sepsis: a systematic review and meta-analysis | Journal of Cardiothoracic Surgery | Springer Nature Link

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