Public Acceptance of Emergency Research Without Prior Consent in Stroke - Report - MDSpire

Public Acceptance of Emergency Research Without Prior Consent in Stroke

  • By

  • Masaru Suzuki

  • Mayumi Fukuda-Doi

  • Haruko Yamamoto

  • Manabu Minami

  • Akiko Ishigami

  • Kanae Hirase

  • Etsuko Arita

  • Takuya Watanabe

  • Koji Iwasaki

  • REFINED-IC Study Group

  • Kazunori Toyoda

  • Masatoshi Koga

  • Manabu Inoue

  • Sohei Yoshimura

  • Yuka Sano

  • Teruyuki Hirano

  • Auko Nemoto

  • Hiroyuki Kawakatsu

  • June 8, 2026

  • 0 min

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Community Attitudes Toward Conducting Emergency Stroke Research Without Informed Consent

Overview

This study investigates public acceptance of emergency research without prospective informed consent (ERWPC) for hyperacute ischemic stroke in Japan.

Background

Informed consent is a fundamental ethical principle in clinical research, ensuring voluntary and well-informed participation. However, in emergency situations like hyperacute ischemic stroke, obtaining consent can be challenging due to the urgent need for treatment. Understanding public attitudes toward ERWPC is important.

Data Highlights

No numerical data or trial data provided in the source material.

Key Findings

['Public acceptance of ERWPC for hyperacute ischemic stroke was assessed through a conjoint analysis.', 'Factors influencing acceptance included decision styles and decision-value orientations.', 'Acceptance of ERWPC may differ from willingness to participate in standard randomized clinical trials.', 'Cultural expectations regarding family involvement in medical decision-making may affect evaluations of ERWPC.', 'Japan lacks a clearly established pathway for ERWPC in hyperacute stroke research.']

Clinical Implications

The findings highlight the need for understanding public perceptions of ERWPC to inform ethical guidelines in emergency research. This understanding may aid in developing frameworks that respect patient autonomy while addressing urgent medical needs.

Conclusion

The study provides empirical insights into public attitudes toward ERWPC, which can inform ongoing discussions about emergency research ethics in Japan and similar contexts.

Related Resources & Content

  1. Critical Care (Springer), 2023 -- Deferred consent in emergency neurocritical research: experience from two prospective cohorts
  2. Intensive Care Medicine, 2007 -- Exploring Deferred Consent in Emergency Critical Care Research: Implications of Early Patient Mortality on Data Utilization
  3. Intensive Care Medicine, 2024 -- Impact of Postponed Consent on Characteristics of Adult Sepsis Patients
  4. The ASCO Post, 2014 -- Informed Consent: Not Just About Blood Tests and Procedures Anymore
  5. 21 CFR 50.24 | Exception from informed consent requirements for emergency research. | eCFR.io
  6. Community consultation for exception from informed consent studies: are market research surveys representative of the target community populations?
  7. 21 CFR 50.24 | Exception from informed consent requirements for emergency research. | eCFR.io
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