Acute retinal necrosis presenting exudative retinal detachment: a case report - Scorecard - MDSpire

Acute retinal necrosis presenting exudative retinal detachment: a case report

  • By

  • Han Wang

  • Ying Zhu

  • Ai Xuan Cheng

  • Chao Zhang

  • June 24, 2026

  • 0 min

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Clinical Scorecard: Exudative Retinal Detachment as an Early Manifestation of Acute Retinal Necrosis: A Case Study

At a Glance

CategoryDetail
ConditionAcute Retinal Necrosis (ARN)
Key MechanismsViral retinitis caused by varicella zoster virus (VZV), leading to exudative retinal detachment.
Target PopulationAdults with acute blurred vision and ocular pain.
Care SettingOphthalmology clinic or hospital setting.

Key Highlights

  • Exudative retinal detachment is a rare early manifestation of ARN.
  • Initial treatment with corticosteroids was administered before confirming VZV infection.
  • Aggressive antiviral therapy led to rapid resolution of retinal detachment.
  • Visual acuity was maintained at 1 month follow-up.
  • Viral infection should be considered in uveitis patients with ERD and poor response to anti-inflammatory therapy.

Guideline-Based Recommendations

Diagnosis

  • Consider metagenomic testing for VZV in cases of atypical retinal detachment.

Management

  • Initiate aggressive combined systemic and intravitreal antiviral therapy along with corticosteroids.

Monitoring & Follow-up

  • Regular follow-up to assess visual acuity and retinal status post-treatment.

Risks

  • Poor prognosis associated with retinal detachment in ARN patients.

Patient & Prescribing Data

43-year-old woman with acute retinal symptoms.

Intravenous acyclovir and intravitreal ganciclovir were critical for treatment.

Clinical Best Practices

  • Early recognition of atypical presentations of ARN is essential.
  • Consider viral causes in patients with ERD and unresponsive to initial therapies.

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