Motor mapping to enable resections of peri-rolandic diffuse gliomas - Scorecard - MDSpire

Motor mapping to enable resections of peri-rolandic diffuse gliomas

  • By

  • James S. Trippett

  • Antonio Dono

  • Syed S. Shams

  • Jaiprakash Gurav

  • Christopher M. Williams

  • Ankush Chandra

  • Yoshua Esquenazi

  • Nitin Tandon

  • July 13, 2026

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Clinical Scorecard: Utilizing Motor Mapping Techniques for Resection of Diffuse Gliomas in the Peri-Rolandic Region

At a Glance

CategoryDetail
ConditionDiffuse Gliomas in the Peri-Rolandic Region
Key MechanismsIntraoperative motor mapping techniques (awake and asleep) for functional preservation during surgical resection.
Target PopulationAdult patients with histologically confirmed diffuse gliomas involving the peri-Rolandic area.
Care SettingNeurosurgical operating room with intraoperative monitoring.

Key Highlights

  • Extent of resection (EOR) is associated with improved overall survival in diffuse glioma patients.
  • Intraoperative motor mapping is the gold standard for functional preservation during glioma resection.
  • Awake motor mapping allows real-time feedback from patients, enhancing precision in identifying eloquent cortex.
  • Asleep motor mapping is performed under general anesthesia using neurophysiological monitoring.
  • Permanent postoperative deficits are defined as new or worsening neurological deficits persisting for 3 months.

Guideline-Based Recommendations

Diagnosis

  • Histological confirmation of diffuse glioma is required for surgical intervention.

Management

  • Utilize intraoperative motor mapping techniques to guide safe and maximal resection.

Monitoring & Follow-up

  • Assess functional status using the Karnofsky Performance Status (KPS) scale pre- and postoperatively.

Risks

  • Postoperative neurological deficits can significantly impact quality of life.

Patient & Prescribing Data

Adult patients with peri-Rolandic diffuse gliomas undergoing resection.

Intraoperative mapping techniques are critical for balancing oncologic outcomes with functional preservation.

Clinical Best Practices

  • Employ both awake and asleep motor mapping based on tumor location and patient suitability.
  • Conduct thorough preoperative imaging to inform surgical planning.

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