Evaluation of ambulance blood cultures in patients with suspected sepsis. A rural prospective cohort study - Scorecard - MDSpire

Evaluation of ambulance blood cultures in patients with suspected sepsis. A rural prospective cohort study

  • By

  • Lars-Jøran Andersson

  • Gunnar Skov Simonsen

  • Erik Solligård

  • Knut Fredriksen

  • May 22, 2026

  • 0 min

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Clinical Scorecard: Assessment of Blood Cultures in Ambulance Settings for Patients with Suspected Sepsis: A Prospective Cohort Study in a Rural Area

At a Glance

CategoryDetail
Condition
Key MechanismsEarly diagnosis and therapy may decrease morbidity and mortality; blood cultures (BCs) guide therapy selection. [Source needed]
Target Population
Care Setting

Key Highlights

  • Positive blood cultures in prehospital settings may guide therapy and improve outcomes. [Source needed]
  • Current practices yield positive cultures in only 11.4% of samples drawn in emergency departments.
  • Ambulance blood culture sampling poses challenges such as contamination risk and time delays.

Guideline-Based Recommendations

Diagnosis

  • Draw two sets of blood cultures before starting intravenous antimicrobial therapy. [Source needed]

Management

  • Start antimicrobial treatment prior to blood cultures if they cannot be obtained in a timely manner. [Source needed]

Monitoring & Follow-up

  • Evaluate the association between positive blood cultures and sepsis severity using the SOFA score. [Source needed]

Risks

  • Increased risk of contamination in prehospital settings may affect diagnostic value. [Source needed]

Patient & Prescribing Data

Patients with suspected sepsis, including children and adults.

Antimicrobial therapy administered according to national guidelines.

Clinical Best Practices

  • Train ambulance personnel in sepsis management and blood culture sampling. [Source needed]
  • Use clinical decision support tools like qSOFA, SIRS, and RETTS scores.

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