Evaluation of ambulance blood cultures in patients with suspected sepsis. A rural prospective cohort study
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By
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Lars-Jøran Andersson
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Gunnar Skov Simonsen
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Erik Solligård
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Knut Fredriksen
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May 22, 2026
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Clinical Scorecard: Assessment of Blood Cultures in Ambulance Settings for Patients with Suspected Sepsis: A Prospective Cohort Study in a Rural Area
At a Glance
| Category | Detail |
| Condition | |
| Key Mechanisms | Early diagnosis and therapy may decrease morbidity and mortality; blood cultures (BCs) guide therapy selection. [Source needed] |
| Target Population | |
| Care Setting | |
Key Highlights
- Positive blood cultures in prehospital settings may guide therapy and improve outcomes. [Source needed]
- Current practices yield positive cultures in only 11.4% of samples drawn in emergency departments.
- Ambulance blood culture sampling poses challenges such as contamination risk and time delays.
Guideline-Based Recommendations
Diagnosis
- Draw two sets of blood cultures before starting intravenous antimicrobial therapy. [Source needed]
Management
- Start antimicrobial treatment prior to blood cultures if they cannot be obtained in a timely manner. [Source needed]
Monitoring & Follow-up
- Evaluate the association between positive blood cultures and sepsis severity using the SOFA score. [Source needed]
Risks
- Increased risk of contamination in prehospital settings may affect diagnostic value. [Source needed]
Patient & Prescribing Data
Patients with suspected sepsis, including children and adults.
Antimicrobial therapy administered according to national guidelines.
Clinical Best Practices
- Train ambulance personnel in sepsis management and blood culture sampling. [Source needed]
- Use clinical decision support tools like qSOFA, SIRS, and RETTS scores.
Related Resources & Content