A hybrid implementation-effectiveness study of a school-based intervention for promoting health and well-being in low-resource settings: the ISOBAR study protocol

Category	Detail
Condition	Non-communicable diseases (NCDs) in adolescents
Key Mechanisms	School-based health promotion interventions addressing mental and physical health
Target Population	Adolescents aged 12-18 years in low-and-middle-income countries (LMICs)
Care Setting	School environments in resource-limited settings

Development of a culturally adapted three-stage composite intervention for physical and mental health
Focus on co-production to ensure intervention suitability to local settings
Research capacity building for future studies in implementation science and health economics
Logistical and ethical constraints prevent randomized controlled trial design
Control condition students receive guidance to local services, potentially affecting intervention outcomes

Assessment for mental health/behavioral problems and nutritional/weight problems at baseline

Implementation of a universal health literacy intervention and indicated counselling for at-risk adolescents

Conducting assessments on intervention effectiveness, implementation processes, and cost-effectiveness

Causal inference limitations due to the absence of a randomized controlled trial design

Adolescents in LMICs, specifically in Chennai, Gujarat (India), and Ibadan (Nigeria)

Intervention includes health literacy and counselling based on pre-determined health thresholds

Clinical Scorecard: A Hybrid Study Protocol for Assessing the Effectiveness of a School-Based Health Promotion Intervention in Resource-Limited Environments: The ISOBAR Project