Acute respiratory distress syndrome and severe pneumonia linked to avian influenza A (H10N3) in a young woman: a case study
By
Mei Zhao
Qiyun Shi
Lin Zhao
Meng Wang
Jingwen Li
Zhiyi Wan
Tun Ouyang
Yang Yu
July 17, 2026
Clinical Scorecard: Acute respiratory distress syndrome and severe pneumonia linked to avian influenza A (H10N3) in a young woman: a case study
At a Glance
Category Detail
Condition Avian influenza A (H10N3) infection Key Mechanisms Zoonotic transmission from infected poultry leading to severe respiratory illness. Target Population Individuals with direct contact with infected poultry or contaminated environments. Care Setting Infectious disease facility and respiratory intensive care unit.
Key Highlights
Only three reported cases of human infection with H10N3 globally. Patient developed severe pneumonia and ARDS after exposure to infected poultry. Metagenomic sequencing confirmed avian influenza A (H10N3) infection. Patient required mechanical ventilation and veno-venous ECMO due to hypoxemia. Patient recovered after three months of intensive treatment. Guideline-Based Recommendations
Diagnosis
Use of RT-PCR and metagenomic next-generation sequencing for confirmation of avian influenza. Management
Empirical antimicrobial therapy and antiviral treatment for confirmed cases. Monitoring & Follow-up
Continuous monitoring of respiratory status and potential complications such as pneumothorax. Risks
High mortality rates associated with severe respiratory illness from avian influenza. Patient & Prescribing Data
Young, previously healthy individuals with exposure to avian influenza.
Combination of antiviral and antifungal therapies along with supportive care in severe cases.
Clinical Best Practices
Early identification and isolation of suspected avian influenza cases. Prompt initiation of antiviral therapy in confirmed cases. Utilization of ECMO in cases of severe hypoxemia. Related Resources & Content
