Acute respiratory distress syndrome and severe pneumonia linked to avian influenza A (H10N3) in a young woman: a case study
-
By
-
Mei Zhao
-
Qiyun Shi
-
Lin Zhao
-
Meng Wang
-
Jingwen Li
-
Zhiyi Wan
-
Tun Ouyang
-
Yang Yu
-
July 17, 2026
Clinical Scorecard: Acute respiratory distress syndrome and severe pneumonia linked to avian influenza A (H10N3) in a young woman: a case study
At a Glance
| Category | Detail |
|---|
| Condition | Avian influenza A (H10N3) infection |
| Key Mechanisms | Zoonotic transmission from infected poultry leading to severe respiratory illness. |
| Target Population | Individuals with direct contact with infected poultry or contaminated environments. |
| Care Setting | Infectious disease facility and respiratory intensive care unit. |
Key Highlights
- Only three reported cases of human infection with H10N3 globally.
- Patient developed severe pneumonia and ARDS after exposure to infected poultry.
- Metagenomic sequencing confirmed avian influenza A (H10N3) infection.
- Patient required mechanical ventilation and veno-venous ECMO due to hypoxemia.
- Patient recovered after three months of intensive treatment.
Guideline-Based Recommendations
Diagnosis
- Use of RT-PCR and metagenomic next-generation sequencing for confirmation of avian influenza.
Management
- Empirical antimicrobial therapy and antiviral treatment for confirmed cases.
Monitoring & Follow-up
- Continuous monitoring of respiratory status and potential complications such as pneumothorax.
Risks
- High mortality rates associated with severe respiratory illness from avian influenza.
Patient & Prescribing Data
Young, previously healthy individuals with exposure to avian influenza.
Combination of antiviral and antifungal therapies along with supportive care in severe cases.
Clinical Best Practices
- Early identification and isolation of suspected avian influenza cases.
- Prompt initiation of antiviral therapy in confirmed cases.
- Utilization of ECMO in cases of severe hypoxemia.
Related Resources & Content
