Efficacy and safety of MuShengshu in the treatment of mild-to-moderate atopic dermatitis: protocol for a randomized, double-blind, placebo-controlled trial - Scorecard - MDSpire

Efficacy and safety of MuShengshu in the treatment of mild-to-moderate atopic dermatitis: protocol for a randomized, double-blind, placebo-controlled trial

  • By

  • Xiangjin Gao

  • Ruiqi Cai

  • Jinrong Lu

  • Zhen Duan

  • Quanruo Xu

  • Xiuqi Zhang

  • Fanlingzi Shen

  • Rui Zhang

  • Bin Li

  • Ruiping Wang

  • May 21, 2026

  • 0 min

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Clinical Scorecard: Assessment of the Safety and Effectiveness of MuShengshu for Mild to Moderate Atopic Dermatitis: A Protocol for a Randomized, Double-Blind, Placebo-Controlled Study

At a Glance

CategoryDetail
Condition
Key MechanismsMuShengshu is a weakly acidic bath solution containing traditional Chinese medicine ingredients that may alleviate pruritus and promote skin healing.
Target Population
Care Setting

Key Highlights

  • Foundational therapies include desonide and triamcinolone acetonide creams, applied concurrently with MuShengshu.

Guideline-Based Recommendations

Diagnosis

    Management

      Monitoring & Follow-up

      • Assess EASI, VAS, IGA, and DLQI at baseline, weeks 1, 2, 4, and 16, with specific criteria for each assessment.

      Risks

        Patient & Prescribing Data

        MSS combined with foundational therapies may enhance treatment efficacy and reduce recurrence; consider potential side effects.

        Clinical Best Practices

        • Incorporate appropriate bathing practices to facilitate skin repair, supported by evidence-based references.
        • Monitor skin barrier function and pH balance in treatment plans.
        • Utilize a combination of topical therapies for comprehensive management.

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        Original Source(s)

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