Assessment of Metabolic Scores for Visceral Fat and the Risk of Cardiovascular Disease in Adults with Stages 0–3 of CKM Syndrome: Findings from a Longitudinal CHARLS Study - Scorecard - MDSpire

Assessment of Metabolic Scores for Visceral Fat and the Risk of Cardiovascular Disease in Adults with Stages 0–3 of CKM Syndrome: Findings from a Longitudinal CHARLS Study

  • By

  • Hao Zhang

  • Shun Li

  • Junpeng Kan

  • Tingting Xia

  • Ning Cao

  • Hui Chen

  • January 17, 2026

  • 0 min

Share

Clinical Scorecard: Assessment of Metabolic Scores for Visceral Fat and the Risk of Cardiovascular Disease in Adults with Stages 0–3 of CKM Syndrome: Findings from a Longitudinal CHARLS Study

At a Glance

CategoryDetail
ConditionCardiovascular-Kidney-Metabolic (CKM) syndrome
Key MechanismsInsulin Resistance (IR) linking visceral adiposity, endothelial dysfunction, and cardiovascular disease (CVD)
Target PopulationAdults with CKM syndrome stages 0–3
Care SettingCommunity-based cohort study

Key Highlights

  • METS-VF integrates multiple metrics to assess visceral fat and metabolic dysfunction.
  • CVD risk increases with CKM syndrome progression from stages 0 to 3.
  • Insulin sensitivity (eGDR) mediates the relationship between METS-VF and CVD.

Guideline-Based Recommendations

Diagnosis

  • Utilize METS-VF for assessing cardiometabolic risk in CKM syndrome.

Management

  • Focus on managing metabolic abnormalities and monitoring visceral fat.

Monitoring & Follow-up

  • Regular follow-ups for incident CVD in CKM syndrome patients.

Risks

  • Increased risk of CVD with advancing CKM syndrome stages.

Patient & Prescribing Data

Adults with CKM syndrome stages 0–3 from the CHARLS cohort.

Targeted interventions should consider metabolic profiles and visceral fat metrics.

Clinical Best Practices

  • Incorporate METS-VF in routine assessments for CKM syndrome.
  • Monitor insulin sensitivity as part of cardiovascular risk management.

References

Original Source(s)

Assessment of Metabolic Scores for Visceral Fat and the Risk of Cardiovascular Disease in Adults with Stages 0–3 of CKM Syndrome: Findings from a Longitudinal CHARLS Study

  • by Hao Zhang, Shun Li, Junpeng Kan, Tingting Xia, Ning Cao, Hui Chen

  • January 17, 2026

Related Content

Audiovisual Augmentation of Electronic Consent to Improve Consent Rates and Comprehension: A Randomized

Correction to: Bariatric Surgery for Patients Living with Obesity and Left Ventricular Dysfunction: Evaluating Perioperative Safety and Postoperative Functional Outcomes

Grip Strength Plus Waist Size May Flag Risk T2D Risk

Researchers found that patients with higher waist circumference and lower grip strength had the greatest risk for developing type 2 diabetes during long-term follow-up.