Performance changes in automated lesion detection under federated learning with sequential institution addition - Scorecard - MDSpire
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Impact of Sequential Institution Integration on Automated Lesion Detection Performance in Federated Learning Systems

  • By

  • Yukihiro Nomura

  • Shouhei Hanaoka

  • Aiki Yamada

  • Tomomi Takenaga

  • Takahiro Nakao

  • Toshiya Nakaguchi

  • Takeharu Yoshikawa

  • Osamu Abe

  • September 27, 2026

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Clinical Scorecard: Impact of Sequential Institution Integration on Automated Lesion Detection Performance in Federated Learning Systems

At a Glance

Category

Detail

Condition

Automated Lesion Detection

Key Mechanisms

Federated Learning, Machine Learning Algorithms

Target Population

Patients undergoing MRI for cerebral aneurysms and brain metastases

Care Setting

Clinical practice utilizing computer-aided detection software

Key Highlights

  • Federated learning allows institutions to train models while retaining local data.

  • Sequential addition of institutions may enhance CAD software performance.

  • Two CAD software types were evaluated: for cerebral aneurysms and brain metastases.

  • Different training approaches were assessed: from-scratch, fine-tuning, and full fine-tuning.

  • Centralized models used pooled training data from participating clients.

Guideline-Based Recommendations

Diagnosis

  • Incorporate data from multiple institutions to improve model robustness.

Management

  • Utilize federated learning frameworks for training CAD systems.

Monitoring & Follow-up

  • Evaluate performance metrics as new institutions are added.

Risks

  • Performance may deteriorate if training data do not match clinical data.

Patient & Prescribing Data

Patients with cerebral aneurysms and brain metastases undergoing MRI.

CAD software can assist in the detection of lesions in MRI images.

Clinical Best Practices

  • Use federated learning to enhance the generalizability of CAD systems.

  • Regularly update models with new data from additional institutions.

Related Resources & Content

  1. Suraj Rajendran et al., ASCO Publications, 2021 -- Cloud-Based Federated Learning Implementation Across Medical Centers

  2. Collaborative 3D segmentation of multiple organs using both labeled and unlabeled datasets, Springer, 2024

  3. Is Federated Learning the Answer to Patient Privacy in AI?, ASCO AI in Oncology, 2026

  4. Transcript for CDRH Webinar Final Guidance: Marketing Submission Recommendations for a Predetermined Change Control Plan for Artificial Intelligence-Enabled Device Software Functions, FDA, 2024

  5. Screening performance and characteristics of breast cancer detected in the Mammography Screening with Artificial Intelligence trial (MASAI), ScienceDirect, 2024

  6. Federated Learning with Contrastive Prototypes for Detecting Fetal Standard Planes Amid Noisy Labels

  7. Transcript for CDRH Webinar Final Guidance: Marketing Submission Recommendations for a Predetermined Change Control Plan for Artificial Intelligence-Enabled Device Software Functions

  8. Screening performance and characteristics of breast cancer detected in the Mammography Screening with Artificial Intelligence trial (MASAI): a randomised, controlled, parallel-group, non-inferiority, single-blinded, screening accuracy study - ScienceDirect

  9. Advancements and challenges of federated learning in medical imaging: a systematic literature review | Artificial Intelligence Review | Springer Nature Link

Original Source(s)

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