Bilateral Synchronous Phyllodes Tumors with Differing Grades and Misleading Axillary 18F-FDG PET-CT Uptake: A Case Study and Review of the Literature - Scorecard - MDSpire
Advertisement
Bilateral Synchronous Phyllodes Tumors with Differing Grades and Misleading Axillary 18F-FDG PET-CT Uptake: A Case Study and Review of the Literature
Clinical Scorecard: Bilateral Synchronous Phyllodes Tumors with Differing Grades and Misleading Axillary 18F-FDG PET-CT Uptake: A Case Study and Review of the Literature
At a Glance
Category
Detail
Condition
Bilateral Synchronous Phyllodes Tumors
Key Mechanisms
Variable biologic behavior; potential for false-positive nodal staging due to inflammation and necrosis.
Target Population
Adult women, particularly those presenting with breast masses.
Care Setting
Breast surgery department in a hospital.
Key Highlights
Phyllodes tumors account for 0.3%-1% of all primary breast tumors.
Synchronous bilateral phyllodes tumors are exceptionally rare.
18F-FDG PET-CT may show false-positive results due to tumor necrosis.
Complete surgical excision with negative margins is crucial for management.
Reactive lymphadenopathy may complicate axillary management.
Guideline-Based Recommendations
Diagnosis
Use imaging and core biopsy to differentiate between fibroadenoma and benign phyllodes tumor.
Management
Perform complete surgical excision with negative margins.
Monitoring & Follow-up
Monitor for recurrence based on histologic grade and margin status.
Risks
Higher local recurrence risk associated with borderline and malignant tumors.
Patient & Prescribing Data
Adult women with phyllodes tumors, particularly those with ulcerated lesions.
Ceftriaxone sodium was administered postoperatively to prevent infection.
Clinical Best Practices
Emphasize clinicopathologic correlation in interpreting axillary FDG uptake.
Individualize axillary management based on clinical findings.
