Effect of remifentanil on parturients and newborns undergoing cesarean section with general anesthesia: a systematic review and a meta-analysis - Scorecard - MDSpire
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Impact of Remifentanil on Maternal and Neonatal Outcomes in Cesarean Deliveries with General Anesthesia: A Systematic Review and Meta-Analysis
Clinical Scorecard: Impact of Remifentanil on Maternal and Neonatal Outcomes in Cesarean Deliveries with General Anesthesia: A Systematic Review and Meta-Analysis
At a Glance
Category
Detail
Condition
Cesarean Delivery with General Anesthesia
Key Mechanisms
Remifentanil is a fast-acting synthetic opioid that stabilizes maternal hemodynamics during anesthesia.
Target Population
Pregnant women undergoing cesarean sections requiring general anesthesia.
Care Setting
Obstetric anesthesia
Key Highlights
Remifentanil group showed lower 1-minute Apgar scores compared to control.
Maternal mean arterial pressure at intubation was significantly lower in the remifentanil group.
No significant differences in 5-minute Apgar scores or other neonatal outcomes.
Guideline-Based Recommendations
Diagnosis
Assess the need for general anesthesia in cesarean deliveries.
Management
Consider remifentanil for maternal hemodynamic stability during general anesthesia.
Monitoring & Follow-up
Monitor neonatal Apgar scores and maternal blood pressure during and after anesthesia.
Risks
Potential for lower 1-minute Apgar scores and respiratory issues in neonates.
Patient & Prescribing Data
Women undergoing cesarean sections under general anesthesia.
Remifentanil may stabilize maternal blood pressure but could affect neonatal outcomes.
Clinical Best Practices
Utilize remifentanil judiciously in general anesthesia for cesarean sections.
Conduct thorough monitoring of both maternal and neonatal outcomes post-anesthesia.
