Case Report: dynamic monocyte reprogramming during ALSS therapy in type B HBV-ACLF revealed by single-cell transcriptomics - Scorecard - MDSpire

Case Report: dynamic monocyte reprogramming during ALSS therapy in type B HBV-ACLF revealed by single-cell transcriptomics

  • By

  • Jiale Xie

  • Jiahua Liu

  • Feiyu Wang

  • Dongxuan Zhang

  • Yuyao Tian

  • Júlio Ken Matsubara

  • Jingxiang Zhang

  • Jie Yin

  • Zian Chen

  • Huimin Liu

  • Xiaoshuang Xu

  • Xin Wang

  • Guifen Liu

  • Jianhua Wang

  • Yansheng Jia

  • Lili Chang

  • Yu Guo

  • Wei Qi

  • Yan Wang

  • May 26, 2026

  • 0 min

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Clinical Scorecard: Case Study: Single-Cell Transcriptomic Analysis Reveals Monocyte Reprogramming Dynamics During ALSS Treatment in Type B HBV-ACLF

At a Glance

CategoryDetail
Condition
Key Mechanisms
Target PopulationYoung male patients with Type B HBV-ACLF.
Care Setting

Key Highlights

  • High mortality risk associated with HBV-ACLF.

Guideline-Based Recommendations

Diagnosis

    Management

      Monitoring & Follow-up

      • Monitor changes in monocyte populations and inflammatory markers, including specific cytokines.

      Risks

        Patient & Prescribing Data

        Young male patient with Type B HBV-ACLF.

        Clinical Best Practices

        • Educate patients on the risks associated with HBV-ACLF.

        Related Resources & Content

        Original Source(s)

        Case Report: dynamic monocyte reprogramming during ALSS therapy in type B HBV-ACLF revealed by single-cell transcriptomics

        • by Jiale Xie, Jiahua Liu, Feiyu Wang, Dongxuan Zhang, Yuyao Tian, Júlio Ken Matsubara, Jingxiang Zhang, Jie Yin, Zian Chen, Huimin Liu, Xiaoshuang Xu, Xin Wang, Guifen Liu, Jianhua Wang, Yansheng Jia, Lili Chang, Yu Guo, Wei Qi, Yan Wang

        • May 26, 2026

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