Cardiometabolic Index: a novel prognostic biomarker for recurrent stroke risk in acute ischemic stroke patients - Scorecard - MDSpire

Cardiometabolic Index: a novel prognostic biomarker for recurrent stroke risk in acute ischemic stroke patients

  • By

  • Yue Wang

  • Yingying Ding

  • Min Han

  • Yehong Liu

  • Tao Xin

  • June 10, 2026

  • 0 min

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Clinical Scorecard: Cardiometabolic Index: An Innovative Prognostic Marker for Assessing Recurrent Stroke Risk in Patients with Acute Ischemic Stroke

At a Glance

CategoryDetail
Condition
Key MechanismsDysregulated lipid metabolism and immune-inflammatory responses (source needed).
Target Population
Care Setting

Key Highlights

  • CMI is a reliable prognostic biomarker for predicting adverse cerebrovascular events in AIS patients post-thrombolysis (source needed).
  • A high CMI value (≥0.80) correlates with increased risk of major adverse cerebrovascular events (MACEs) (source needed).
  • Systemic inflammation partially mediates the predictive effect of CMI on adverse outcomes (source needed).
  • CMI outperforms traditional biomarkers in predicting long-term outcomes for AIS patients (source needed).

Guideline-Based Recommendations

Diagnosis

  • Utilize CMI as a prognostic marker for assessing recurrent stroke risk (source needed).

Management

  • Incorporate CMI in risk stratification and individualized treatment strategies for AIS patients (source needed).

Monitoring & Follow-up

  • Monitor CMI values to assess the risk of MACEs in post-thrombolytic therapy patients (source needed).

Risks

  • High CMI values are associated with increased risk of recurrent strokes and adverse cerebrovascular events (source needed).

Patient & Prescribing Data

588 patients with Acute Ischemic Stroke who underwent thrombolytic therapy.

CMI reflects both metabolic and inflammatory status, aiding in the optimization of post-discharge care.

Clinical Best Practices

  • Employ CMI for comprehensive risk assessment in AIS patients (source needed).
  • Consider systemic inflammation markers alongside CMI for better prognostic accuracy (source needed).

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Original Source(s)

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