Alcohol and Other Substance Screening in Bariatric Surgery Candidates: Utility of Self-Report and Toxicology Tests, Including Ethyl-Glucoronide - Scorecard - MDSpire

Alcohol and Other Substance Screening in Bariatric Surgery Candidates: Utility of Self-Report and Toxicology Tests, Including Ethyl-Glucoronide

  • By

  • Silvia Cañizares

  • Laura Nuño

  • Pablo Barrio

  • Mireia Forner-Puntonet

  • Carolina Gavotti

  • Miquel Monràs

  • Patricia Gavín

  • Ricard Navinés

  • Lilliam Flores

  • Maite Barrios

  • Alba Andreu

  • Judit Molero

  • Amanda Jimenez

  • Josep Vidal

  • Anna Lligoña

  • March 12, 2025

  • 0 min

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Clinical Scorecard: Evaluating Alcohol and Substance Use in Candidates for Bariatric Surgery: The Role of Self-Reported Data and Toxicology Assessments, Including Ethyl-Glucuronide

At a Glance

CategoryDetail
ConditionAlcohol and substance use in bariatric surgery candidates
Key MechanismsAssessment of risky alcohol consumption and substance use via self-report questionnaires and urine toxicology including ethyl glucuronide (EtG) biomarker
Target PopulationCandidates for primary bariatric surgery at a tertiary hospital obesity unit
Care SettingPreoperative psychological evaluation in a tertiary hospital obesity unit

Key Highlights

  • Risky drinking defined as >2 standard drinks/day or >4 on a single occasion, increasing risk of alcohol use disorder (AUD).
  • Use of validated screening tools (AUDIT-C, ASSIST) combined with urine EtG and drug testing enhances detection of alcohol and substance use.
  • 4% of candidates met criteria for alcohol abuse and 2% for dependence; 33% had a current Axis I psychiatric disorder, with major depressive disorder most common.

Guideline-Based Recommendations

Diagnosis

  • Include alcohol and substance use assessment in preoperative psychological evaluation for bariatric surgery candidates.
  • Use validated questionnaires such as AUDIT-C for risky alcohol use and ASSIST for substance involvement screening.
  • Employ objective biomarkers like urine ethyl glucuronide (EtG) to detect recent alcohol consumption up to 72 hours.
  • Screen for psychiatric comorbidities using structured interviews like the MINI.

Management

  • Identify and address risky drinking and substance use prior to bariatric surgery to optimize outcomes.
  • Consider psychopharmacological treatment needs as 32% of candidates were on antidepressants and 28% on benzodiazepines.
  • Provide targeted interventions for patients with diagnosed AUD or other substance use disorders.

Monitoring & Follow-up

  • Use urine toxicology including EtG and drug screening to monitor alcohol and substance use during preoperative assessment.
  • Regularly reassess alcohol and substance use patterns postoperatively due to increased risk of AUD development.

Risks

  • Risky alcohol use negatively impacts weight loss and nutritional status post-bariatric surgery.
  • Increased risk of developing alcohol use disorder after bariatric surgery in a subset of patients.
  • Undetected substance use may complicate surgical outcomes and postoperative care.

Patient & Prescribing Data

Bariatric surgery candidates with obesity and comorbid psychiatric conditions

High prevalence of psychopharmacological treatment: 32% antidepressants, 28% benzodiazepines, 17% opioids, 5% antipsychotics, indicating need for integrated psychiatric and substance use management.

Clinical Best Practices

  • Combine self-reported questionnaires with objective urine biomarkers (EtG) for comprehensive alcohol use assessment.
  • Screen for both alcohol and other substance use systematically in bariatric surgery candidates.
  • Incorporate psychiatric evaluation to identify comorbid mental health disorders influencing substance use.
  • Use hierarchical logistic regression to identify predictive factors for risky drinking to tailor interventions.

References

Original Source(s)

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