The interplay between epidermal cells and the cutaneous sensory nervous: a systematic review
By
Feifei Wang
Xiaohong An
Dongjie Fan
Jing Shang
May 26, 2026
Clinical Scorecard: Exploring the Relationship Between Epidermal Cells and Cutaneous Sensory Nerves: A Comprehensive Review
At a Glance
Category Detail
Condition Key Mechanisms Target Population Individuals with cutaneous disorders and neurological diseases, including those with comorbid conditions. Care Setting
Key Highlights
Chronic cutaneous pathologies may exacerbate neurological dysfunctions and vice versa, impacting mental health. Guideline-Based Recommendations
Diagnosis
Management
Consider the role of sensory nerves in chronic inflammation and pain perception when treating dermatological conditions. Incorporate specific treatment modalities for chronic inflammation. Monitoring & Follow-up
Risks
Patient & Prescribing Data
Epidermal cells can produce bioactive substances, such as cytokines and neuropeptides, that modulate sensory nerve activity.
Clinical Best Practices
Utilize a multidisciplinary approach involving dermatology and neurology for comprehensive patient care. Educate patients on the interplay between skin health and neurological function, providing specific educational materials. Related Resources & Content
