Trajectories of Physical Function in Canadian Children With Juvenile Idiopathic Arthritis - Scorecard - MDSpire
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Patterns of Physical Function in Canadian Youth Diagnosed with Juvenile Idiopathic Arthritis

  • By

  • Clare Cunningham

  • Meghan McPherson

  • Lillian Lim

  • Roberta A. Berard

  • Matthew Berkowitz

  • Jean-Philippe Proulx-Gauthier

  • Brian M. Feldman

  • Nicole Johnson

  • Dax G. Rumsey

  • Heinrike Schmeling

  • Lori B. Tucker

  • Thomas Loughin

  • Kristin M. Houghton

  • Jaime Guzman

  • May 14, 2026

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Clinical Scorecard: Patterns of Physical Function in Canadian Youth Diagnosed with Juvenile Idiopathic Arthritis

At a Glance

CategoryDetail
ConditionJuvenile Idiopathic Arthritis (JIA)
Key MechanismsChronic rheumatic disease leading to pain, joint swelling, and functional impairments.
Target PopulationChildren and adolescents diagnosed with JIA.
Care SettingPediatric rheumatology clinics across Canada.

Key Highlights

  • Most children had mild to moderate functional impairments at diagnosis, improving within 36 weeks.
  • Rheumatoid factor-positive polyarthritis had the largest functional impact.
  • 38% of patients had persisting mild functional impairments identified by a baseline Kids Disability Screen ≥1.5.
  • 8% reported moderate to severe impairment at least once beyond two years after diagnosis.
  • Achievement of clinically inactive disease increased from 64% to 83% in recent cohorts.

Guideline-Based Recommendations

Diagnosis

  • Utilize the International League of Associations for Rheumatology (ILAR) criteria for classification.

Management

  • Implement physiotherapy and occupational therapy to improve function and participation.

Monitoring & Follow-up

  • Regular assessments using the Kids Disability Screen (KDS) to track functional status.

Risks

  • Potential for lifelong disability and functional limitations if not addressed early.

Patient & Prescribing Data

Children diagnosed with JIA before the age of 16 years.

Modern treatments include conventional synthetic, targeted synthetic, and biologic DMARDs.

Clinical Best Practices

  • Introduce services addressing function closer to disease onset.
  • Focus on preventive measures to improve long-term outcomes.

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