An evaluation of factors associated with hypertension in children and adolescents with obesity
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By
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Zhou, Kexin
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Cai, Zili
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Xiang, Shiting
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Wei, Jianhui
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Deng, Manxin
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Peng, Yunlong
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Liu, Zhiyu
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Tan, Jie
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Zhu, Guanghui
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Gong, Zhuo
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Li, Qi
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Zhu, Lemei
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Qiu, Jun
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April 30, 2026
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Clinical Scorecard: Assessing Risk Factors for Hypertension in Obese Children and Adolescents
At a Glance
| Category | Detail |
|---|
| Condition | Hypertension in Obese Children |
| Key Mechanisms | Elevated levels of neutrophils, NLR, platelet count, albumin, and triglycerides are associated with hypertension. |
| Target Population | Children with obesity aged approximately 11.9 years. |
| Care Setting | Child Health Development Center, Hunan Children’s Hospital |
Key Highlights
- Detection rate of hypertension in obese children is 20.6%.
- Mean age of participants is 11.9±2.0 years.
- Neutrophils, NLR, PLT, ALB, and TG are independent risk factors for hypertension.
- Significant linear relationship between NE, NLR, ALB, TG and blood pressure.
- Nonlinear dose-response relationship observed between PLT and SBP.
Guideline-Based Recommendations
Diagnosis
- Monitor blood pressure in children with obesity.
Management
- Address elevated levels of NE, NLR, PLT, ALB, and TG.
Monitoring & Follow-up
- Regular assessment of blood pressure and associated risk factors.
Risks
- Increased risk of hypertension associated with obesity.
Patient & Prescribing Data
Children with obesity.
Focus on managing identified risk factors such as elevated NE, NLR, PLT, ALB, and TG.
Clinical Best Practices
- Implement routine blood pressure checks in obese pediatric patients.
- Evaluate and manage metabolic risk factors in children with obesity.
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