Risk factors for refractory BPPV: subtype-dependent association of serum 25-hydroxyvitamin D
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By
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Hye Ah Joo
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Sun A. Han
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Jin Kim
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Il-Seok Park
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Min Young Kwak
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June 3, 2026
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Clinical Scorecard: Identifying Risk Factors for Refractory BPPV: The Role of Serum 25-Hydroxyvitamin D Levels in Different Subtypes
At a Glance
| Category | Detail |
|---|
| Condition | |
| Key Mechanisms | Displacement of otoconia from the utricular or saccular macula; serum 25-hydroxyvitamin D levels may be associated with otoconial stability. |
| Target Population | |
| Care Setting | |
Key Highlights
- BPPV subtype and prior vestibular neuritis were identified as predictors of treatment resistance.
Guideline-Based Recommendations
Diagnosis
Management
Monitoring & Follow-up
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Risks
Patient & Prescribing Data
Patients with acute BPPV, excluding those with central lesions or secondary BPPV.
Refractory cases may require multiple CRP attempts, with a plateau in resolution after three attempts.
Clinical Best Practices
- Assess serum 25(OH)D levels in relation to BPPV treatment resistance, as indicated by the findings.
Related Resources & Content
