Heel hidradenocarcinoma regarded as a corn for 25 years with subsequent multiorgan metastasis: a case report and literature review - Scorecard - MDSpire
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Hidradenocarcinoma of the heel misdiagnosed as a corn for 25 years leading to multiorgan metastasis: a case study and review of existing literature

  • By

  • Lianbo Yang

  • Ziang Zheng

  • Haoran Chen

  • Xinyao Cui

  • Jiabin Lin

  • Yifan Wang

  • Haidong Liang

  • Jing Yi

  • August 14, 2026

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Clinical Scorecard: Hidradenocarcinoma of the heel misdiagnosed as a corn for 25 years leading to multiorgan metastasis: a case study and review of existing literature

At a Glance

CategoryDetail
ConditionHidradenocarcinoma
Key MechanismsMalignant tumor of cutaneous adnexa with sweat-gland differentiation.
Target PopulationPatients with acral lesions, particularly those misdiagnosed or with persistent, enlarging, ulcerated lesions.
Care SettingOncology and surgical pathology.

Key Highlights

  • Hidradenocarcinoma can be misdiagnosed as benign conditions like corns.
  • Complete surgical excision is crucial for localized disease management.
  • Histopathological examination is essential for accurate diagnosis.
  • Metastatic disease can develop in a significant proportion of patients.
  • Individualized treatment approaches are necessary due to limited evidence.

Guideline-Based Recommendations

Diagnosis

  • Histopathological examination is necessary for definitive diagnosis.

Management

  • Complete surgical excision with histologically negative margins is the primary treatment.

Monitoring & Follow-up

  • Regular follow-up for persistent or recurrent lesions is recommended.

Risks

  • Potential for metastasis, particularly in cases with delayed diagnosis.

Patient & Prescribing Data

Patients with hidradenocarcinoma, particularly those with delayed diagnosis.

Combination therapies may be required for metastatic disease, with careful monitoring of side effects.

Clinical Best Practices

  • Timely pathological assessment for acral lesions is essential.
  • Consideration of regional staging and individualized treatment plans.

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