Dengue Fever Among Children in the French Caribbean Amidst an Epidemic
By
Arthur Felix
Zein Assad
Margaux Blanche
Pascale Richard
Dominique Rousset
Thomas Poussot
Julie Gestel
Vincent Genest
Pierre Lortholary
Remi Mutricy
Narcisse Elenga
Julien Denis
Lindsay Osei
July 20, 2026
Clinical Scorecard: Dengue Fever Among Children in the French Caribbean Amidst an Epidemic
At a Glance
Category Detail
Condition Dengue Fever Key Mechanisms Dengue virus (DENV) infection, particularly DENV-2 and DENV-3 serotypes. Target Population Children under 18 years, particularly those with sickle cell disease (SCD). Care Setting Pediatric emergency departments in tertiary hospitals.
Key Highlights
12.6% of pediatric ED consultations for fever were confirmed dengue cases. SCD significantly increased the risk of hospitalization (OR, 15.15). Case fatality rate was 0.4%, lower than in other regions. Intravenous infusion required in 38% of cases. DENV-2 was the predominant serotype in Martinique. Guideline-Based Recommendations
Diagnosis
Dengue fever diagnosed using RT-PCR, DENV IgM antibodies, or NS1 antigen. Management
Early emergency assessment and hydration for children with SCD. Monitoring & Follow-up
Monitor for dehydration and plasma leakage in children with SCD. Risks
Children with SCD are at increased risk for severe outcomes. Patient & Prescribing Data
Pediatric patients aged <18 years presenting with confirmed dengue fever.
Intravenous infusion was necessary for a significant proportion of patients.
Clinical Best Practices
Implement universal neonatal SCD screening. Ensure access to pediatric emergency care for dengue management. Consider vaccination strategies for dengue in high-risk populations. Related Resources & Content
