Experiences in Clinical Implementation of Online Adaptive Radiotherapy for Prostate Cancer: Enhancing Treatment Efficiency
By
Hanna Malygina
Bryan Salazar Zuniga
Hendrik Auerbach
Marc Ries
Sven Knobe
Yvonne Dzierma
Jan Palm
Markus Hecht
February 19, 2026
Clinical Scorecard: Experiences in Clinical Implementation of Online Adaptive Radiotherapy for Prostate Cancer: Enhancing Treatment Efficiency
At a Glance
Category Detail
Condition Prostate Cancer Key Mechanisms Online adaptive radiotherapy (oART) adapts treatment plans based on daily anatomical changes. Target Population Patients with primary prostate cancer, ECOG performance score 0-1. Care Setting Outpatient radiotherapy clinics.
Key Highlights
oART improves target coverage and spares organs at risk compared to non-adaptive approaches. Automated posterior rectal wall contouring significantly reduces adaptation time. CBCT-guided oART offers shorter session times than MR-guided systems. Varian HyperSight enhances imaging speed and quality, facilitating quicker adaptations. Clinical implementation requires optimized workflows and staff training. Guideline-Based Recommendations
Diagnosis
Use imaging and clinical assessment to confirm prostate cancer diagnosis. Management
Implement oART for improved treatment efficiency and patient outcomes. Monitoring & Follow-up
Track adaptation times and treatment outcomes to assess workflow efficiency. Risks
Consider potential delays in physician availability during adaptation. Patient & Prescribing Data
69 patients with primary prostate cancer treated with 20 fractions.
Utilized simultaneous integrated boosts (SIB) based on in-house protocol.
Clinical Best Practices
Incorporate automated contouring to streamline workflow. Upgrade imaging systems to enhance acquisition speed and quality. Train staff thoroughly on oART workflows to ensure efficiency. References
