Transcranial magnetic stimulation-based evaluation of exercise training-induced changes in TMS-derived neurophysiological markers and motor performance in healthy adults: a systematic review and meta-analysis of RCTs - Scorecard - MDSpire
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Transcranial magnetic stimulation-based evaluation of exercise training-induced changes in TMS-derived neurophysiological markers and motor performance in healthy adults: a systematic review and meta-analysis of RCTs
Clinical Scorecard: Evaluation of Neurophysiological Changes and Motor Performance in Healthy Adults Following Exercise Training: A Systematic Review and Meta-Analysis of Randomized Controlled Trials Using Transcranial Magnetic Stimulation
At a Glance
Category
Detail
Condition
Neurophysiological changes and motor performance
Key Mechanisms
Transcranial magnetic stimulation (TMS) assessing corticospinal excitability and intracortical inhibition/facilitation
Target Population
Healthy adults (≥18 years)
Care Setting
Human motor and systems neuroscience
Key Highlights
Twelve randomized controlled trials included in the analysis.
Significant pooled effects for TMS-derived neurophysiological markers (Hedges' g = 0.53).
Significant pooled effects for motor performance (Hedges' g = 0.58).
Moderate heterogeneity observed for both outcomes.
Current evidence insufficient to establish superiority of specific training modalities.
Guideline-Based Recommendations
Diagnosis
Management
Monitoring & Follow-up
Risks
Patient & Prescribing Data
Healthy adults participating in structured exercise training interventions.
Exercise training may improve motor performance and modulate TMS-derived neurophysiological markers.
Clinical Best Practices
Conduct adequately powered randomized controlled trials to confirm findings.
Standardize training protocols to reduce heterogeneity in outcomes.
