Research progress of quercetin in infection at the maternal-fetal interface
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By
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Jiena Shi
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Jili Zhang
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Wenjie Gong
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Longhui Shen
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May 28, 2026
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Clinical Scorecard: Advancements in Understanding Quercetin's Role in Maternal-Fetal Infection Management
At a Glance
| Category | Detail |
| Condition | |
| Key Mechanisms | Regulation of decidual immune cells, balancing cytokine networks, targeting pathogenic signaling pathways, enhancing barrier function of trophoblasts and decidual stromal cells. |
| Target Population | |
| Care Setting | |
Key Highlights
- Infection at the maternal-fetal interface can lead to adverse pregnancy outcomes.
- Current treatments primarily rely on antibiotics and immunomodulators, which have limitations.
- A comprehensive understanding of quercetin's mechanisms in this context is lacking.
Guideline-Based Recommendations
Diagnosis
Management
- Consider quercetin as a potential adjunct therapy for infection management, based on further research.
Monitoring & Follow-up
Risks
Patient & Prescribing Data
Further research is needed to evaluate quercetin's role in treatment.
Clinical Best Practices
- Evaluate the immune status at the maternal-fetal interface.
- Monitor for adverse effects and efficacy in pregnant patients.
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