Rapunzel Syndrome Masks Weight Loss
Researchers identify an extensive trichobezoar in a child with progressive weight loss and feeding changes.
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By
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Kathryn Wighton
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February 23, 2026
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Clinical Scorecard: Rapunzel Syndrome Masks Weight Loss
At a Glance
| Category | Detail |
| Condition | Rapunzel Syndrome |
| Key Mechanisms | Trichobezoar formation due to trichotillomania and trichophagia |
| Target Population | Pediatric patients, particularly adolescents with psychiatric disorders |
| Care Setting | Pediatric emergency and surgical care |
Key Highlights
- Characterized by a large trichobezoar extending from the stomach into the small intestine
- Associated with significant weight loss and abdominal pain
- May lead to obstruction or perforation if untreated
- Diagnosis can be delayed due to underlying psychiatric conditions
- Postoperative management includes dietary supervision and behavioral therapy
Guideline-Based Recommendations
Diagnosis
- Consider Rapunzel syndrome in pediatric patients with unexplained weight loss and abdominal symptoms
Management
- Surgical removal of the trichobezoar is necessary
- Gradual reintroduction of oral feeding under dietetic supervision
Monitoring & Follow-up
- Follow-up for weight improvement and resolution of abdominal symptoms
Risks
- Potential for obstruction or perforation if not treated
Patient & Prescribing Data
10-year-old girl with ADHD and sensory aversion to food textures
Behavioral therapy for trichotillomania and trichophagia is essential
Clinical Best Practices
- Early recognition of symptoms in pediatric patients
- Multidisciplinary approach involving surgery, dietetics, and psychology
References