Psychological Depression and Its Association with Oocyte Yield and Embryo Outcomes in Infertile Women Undergoing In Vitro Fertilization-Embryo Transfer - Scorecard - MDSpire

Psychological Depression and Its Association with Oocyte Yield and Embryo Outcomes in Infertile Women Undergoing In Vitro Fertilization-Embryo Transfer

  • By

  • Song, Xiaohuan

  • Yin, Yitao

  • Jia, Yuedi

  • Wang, Jieyu

  • Wang, Danni

  • April 30, 2026

  • 0 min

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Clinical Scorecard: The Relationship Between Psychological Depression and Oocyte Production and Embryo Success Rates in Infertile Women Undergoing IVF-Embryo Transfer

At a Glance

CategoryDetail
ConditionInfertility and Psychological Depression
Key MechanismsDepressive symptoms impact reproductive outcomes during IVF-ET.
Target PopulationInfertile women undergoing IVF-ET
Care SettingReproductive Medicine Center

Key Highlights

  • 18.1% of participants had moderate to severe depressive symptoms.
  • Higher PHQ-9 scores correlated with fewer transferable embryos.
  • Depression severity negatively affects IVF-related reproductive outcomes.
  • Oocyte retrieval showed borderline significance related to depression.
  • No evidence of nonlinearity in the dose-response relationship.

Guideline-Based Recommendations

Diagnosis

  • Assess depressive symptoms using the Patient Health Questionnaire-9 (PHQ-9) prior to treatment.

Management

  • Consider mental health support for women undergoing IVF-ET.

Monitoring & Follow-up

  • Monitor reproductive outcomes in relation to mental health status.

Risks

  • Increased depressive symptoms may lead to reduced embryo transfer success.

Patient & Prescribing Data

Infertile women undergoing IVF-ET at a reproductive medicine center.

Mental health status is crucial for optimizing IVF outcomes.

Clinical Best Practices

  • Incorporate mental health assessments in fertility treatment protocols.
  • Provide psychological support to patients undergoing IVF-ET.

Related Resources & Content

Original Source(s)

Psychological Depression and Its Association with Oocyte Yield and Embryo Outcomes in Infertile Women Undergoing In Vitro Fertilization-Embryo Transfer

  • by Song, Xiaohuan , Yin, Yitao , Jia, Yuedi , Wang, Jieyu , Wang, Danni

  • April 30, 2026

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