Low admission pulse pressure and increased in-hospital mortality in patients with heart failure
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By
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Liying Zhong
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Meng Wei
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Xianhui Zhou
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April 30, 2026
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Clinical Scorecard: Reduced admission pulse pressure linked to higher in-hospital mortality rates in heart failure patients
At a Glance
| Category | Detail |
|---|
| Condition | Heart Failure |
| Key Mechanisms | Low admission pulse pressure (PP) predicts increased risk of in-hospital mortality and cardiac death. |
| Target Population | Patients with heart failure admitted to the hospital. |
| Care Setting | Inpatient care at a tertiary medical center. |
Key Highlights
- Low admission PP (<30 mmHg) is an independent predictor of in-hospital mortality.
- 7.1% of the studied cohort experienced in-hospital mortality.
- The relationship between PP and mortality is consistent across different left-ventricular ejection fraction (LVEF) phenotypes.
Guideline-Based Recommendations
Diagnosis
- Assess admission pulse pressure as part of the initial evaluation of heart failure patients.
Management
- Integrate pulse pressure into early risk-stratification algorithms for heart failure patients.
Monitoring & Follow-up
- Intensified monitoring for patients with low admission pulse pressure.
Risks
- Patients with PP <50 mmHg have a higher risk of in-hospital mortality.
Patient & Prescribing Data
Adults aged ≥18 years with a primary or secondary diagnosis of heart failure.
Low PP indicates a need for closer observation and potential intervention.
Clinical Best Practices
- Utilize pulse pressure as a key clinical parameter in risk assessment for heart failure patients.
- Consider the implications of pulse pressure in treatment planning and patient management.
References
