Uncommon Case of Disseminated Talaromyces marneffei Infection Manifesting as Acute Pancreatitis in a Patient with HIV-1 - Scorecard - MDSpire

Uncommon Case of Disseminated Talaromyces marneffei Infection Manifesting as Acute Pancreatitis in a Patient with HIV-1

  • By

  • Yanqi Peng

  • Mi Zhang

  • Dandan Yang

  • Yuanlu Shu

  • Jincheng Lou

  • Hongli Fan

  • Zhenglun Li

  • Suyun Lei

  • Xingqi Dong

  • Li Gao

  • December 23, 2025

  • 0 min

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Clinical Scorecard: Uncommon Case of Disseminated Talaromyces marneffei Infection Manifesting as Acute Pancreatitis in a Patient with HIV-1

At a Glance

CategoryDetail
Condition
Key Mechanisms
Target PopulationImmunocompromised individuals, especially those with HIV-1/AIDS in Southeast Asia and Southern China.
Care Setting

Key Highlights

  • CD4_count

Guideline-Based Recommendations

Diagnosis

    Management

    • Initiate empirical antifungal therapy in suspected cases of Talaromyces marneffei infection, considering agents like voriconazole or itraconazole based on clinical response.

    Monitoring & Follow-up

      Risks

        Patient & Prescribing Data

        Switch antifungal therapy based on clinical response and laboratory findings, particularly if initial therapy is ineffective.

        Clinical Best Practices

        • Maintain high suspicion for Talaromyces marneffei in HIV/AIDS patients with atypical presentations and ensure early molecular identification to guide treatment.

        References

        Original Source(s)

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