Deep Learning Algorithms Versus Radiologists in Digital Breast Tomosynthesis for Breast Cancer Detection: Systematic Review and Meta-Analysis - Scorecard - MDSpire

Deep Learning Algorithms Versus Radiologists in Digital Breast Tomosynthesis for Breast Cancer Detection: Systematic Review and Meta-Analysis

  • By

  • Shewen Lyu

  • Zepeng Wang

  • Yujing Mu

  • Luyao Wang

  • Xiaohua Pei

  • May 6, 2026

  • 0 min

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Clinical Scorecard: Comparative Analysis of Deep Learning Models and Radiologists in Detecting Breast Cancer via Digital Breast Tomosynthesis: A Systematic Review and Meta-Analysis

At a Glance

CategoryDetail
ConditionBreast Cancer
Key MechanismsDeep Learning algorithms enhance lesion detection and classification in Digital Breast Tomosynthesis (DBT).
Target PopulationWomen undergoing breast cancer screening via DBT.
Care SettingClinical settings utilizing DBT for breast cancer screening.

Key Highlights

  • DBT improves cancer detection rates and reduces unnecessary recalls.
  • Deep Learning algorithms show potential but face challenges with false positives and generalizability.
  • The performance of DL algorithms varies against radiologists of different experience levels.

Guideline-Based Recommendations

Diagnosis

  • Utilize DBT for improved detection of breast cancer.

Management

  • Incorporate DL algorithms to assist radiologists in interpreting DBT images.

Monitoring & Follow-up

  • Regularly assess the performance of DL algorithms and radiologists in clinical practice.

Risks

  • Be aware of the potential for false positives and negatives in both DL and radiologist interpretations.

Patient & Prescribing Data

Women screened for breast cancer using DBT.

Early and accurate detection through DBT can reduce the burden of invasive treatments.

Clinical Best Practices

  • Adopt a multidisciplinary approach combining DL and radiologist expertise.
  • Ensure continuous training and assessment of radiologists interpreting DBT.

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